دورية أكاديمية
Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography
العنوان: | Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography |
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المؤلفون: | Hwi Seung Kim, Jiwoo Lee, Eun Hee Kim, Min Jung Lee, In Young Bae, Woo Je Lee, Joong-Yeol Park, Hong-Kyu Kim, Chang Hee Jung |
المصدر: | Diabetes & Metabolism Journal, Vol 47, Iss 1, Pp 104-117 (2023) |
بيانات النشر: | Korean Diabetes Association, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
مصطلحات موضوعية: | adipose tissue, liver cirrhosis, muscle, skeletal, non-alcoholic fatty liver disease, sarcopenia, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
الوصف: | Background The association of myosteatosis measured using visual muscular quality map in computed tomography (CT) with nonalcoholic fatty liver disease (NAFLD), its severity, and fibrosis was analyzed in a large population. Methods Subjects (n=13,452) with abdominal CT between 2012 and 2013 were measured total abdominal muscle area (TAMA) at L3 level. TAMA was segmented into intramuscular adipose tissue and skeletal muscle area (SMA), which was further classified into normal attenuation muscle area (NAMA) and low attenuation muscle area (LAMA). The following variables were adopted as indicators of myosteatosis: SMA/body mass index (BMI), NAMA/BMI, NAMA/TAMA, and LAMA/BMI. NAFLD and its severity were assessed by ultrasonography, and liver fibrosis was measured by calculating the NAFLD fibrosis score (NFS) and fibrosis-4 index (FIB-4) scores. Results According to multiple logistic regression analyses, as quartiles of SMA/BMI, NAMA/BMI, and NAMA/TAMA increased, the odds ratios (ORs) for NAFLD decreased in each sex (P for trend |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2233-6079 2233-6087 |
Relation: | http://www.e-dmj.org/upload/pdf/dmj-2022-0081.pdf; https://doaj.org/toc/2233-6079; https://doaj.org/toc/2233-6087 |
DOI: | 10.4093/dmj.2022.0081 |
URL الوصول: | https://doaj.org/article/6a1e74de9c004d24994056e0a71e4301 |
رقم الأكسشن: | edsdoj.6a1e74de9c004d24994056e0a71e4301 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22336079 22336087 |
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DOI: | 10.4093/dmj.2022.0081 |