Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale

التفاصيل البيبلوغرافية
العنوان:	Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale
المؤلفون:	Deepanwita Banerjee, Thomas Eng, Andrew K. Lau, Yusuke Sasaki, Brenda Wang, Yan Chen, Jan-Philip Prahl, Vasanth R. Singan, Robin A. Herbert, Yuzhong Liu, Deepti Tanjore, Christopher J. Petzold, Jay D. Keasling, Aindrila Mukhopadhyay
المصدر:	Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
بيانات النشر:	Nature Portfolio, 2020.
سنة النشر:	2020
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	The trade-off between growth and production affects the application of engineered microbes. Here, the authors take the minimal cut set approach to predict metabolic reactions for elimination to couple metabolite production strongly with growth and achieve high production of indigoidine in Pseudomonas putida.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-020-19171-4
URL الوصول:	https://doaj.org/article/6acc596583b948d89ae284839178e123
رقم الأكسشن:	edsdoj.6acc596583b948d89ae284839178e123
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-020-19171-4