دورية أكاديمية
Demonstration of the Rationale for Therapeutic Drug Monitoring of Isavuconazole: A Case Report with a Lung Transplant Recipient
| العنوان: | Demonstration of the Rationale for Therapeutic Drug Monitoring of Isavuconazole: A Case Report with a Lung Transplant Recipient |
|---|---|
| المؤلفون: | Eliška Dvořáčková, Andrea Zajacová, Jan Havlín, Eva Klapková, Robert Lischke, Ondřej Slanař, Martin Šíma |
| المصدر: | Prague Medical Report, Vol 124, Iss 4, Pp 444-448 (2023) |
| بيانات النشر: | Karolinum Press, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | Medicine, Medicine (General), R5-920 |
| الوصف: | Mucormycosis is a rare invasive fungal disease diagnosed in immunocompromised patients, including those with diabetes or iron overload, and in patients treated for hematological malignancies or after transplantation. Isavuconazole is a triazole antifungal effective against Mucorales with good tolerability, but with potential for relatively high interindividual variability in pharmacokinetics. This report demonstrates the case of a lung transplant recipient treated with isavuconasole that exhibits a very long elimination half-life of 159 hours, and discusses the practical implications of this finding for dosage adjustment and need for therapeutic drug monitoring. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2336-2936 1214-6994 23362936 |
| Relation: | https://pmr.lf1.cuni.cz/124/4/0444/; https://doaj.org/toc/1214-6994; https://doaj.org/toc/2336-2936 |
| DOI: | 10.14712/23362936.2023.34 |
| URL الوصول: | https://doaj.org/article/6b4f03535b3c4ed2afec2b5fbe90460d |
| رقم الأكسشن: | edsdoj.6b4f03535b3c4ed2afec2b5fbe90460d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23362936 12146994 |
|---|---|
| DOI: | 10.14712/23362936.2023.34 |