دورية أكاديمية
Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational studyResearch in context
| العنوان: | Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational studyResearch in context |
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| المؤلفون: | Floor W. Hiemstra, Dirk Jan Stenvers, Andries Kalsbeek, Evert de Jonge, David J. van Westerloo, Laura Kervezee |
| المصدر: | EBioMedicine, Vol 104, Iss , Pp 105169- (2024) |
| بيانات النشر: | Elsevier, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | Intensive care, Critical illness, Glucose, Enteral nutrition, Daily variation, Circadian rhythm, Medicine, Medicine (General), R5-920 |
| الوصف: | Summary: Background: The circadian timing system coordinates daily cycles in physiological functions, including glucose metabolism and insulin sensitivity. Here, the aim was to characterise the 24-h variation in glucose levels in critically ill patients during continuous enteral nutrition after controlling for potential sources of bias. Methods: Time-stamped clinical data from adult patients who stayed in the Intensive Care Unit (ICU) for at least 4 days and received enteral nutrition were extracted from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Linear mixed-effects and XGBoost modelling were used to determine the effect of time of day on blood glucose values. Findings: In total, 207,647 glucose measurements collected during enteral nutrition were available from 6,929 ICU patients (3,948 males and 2,981 females). Using linear mixed-effects modelling, time of day had a significant effect on blood glucose levels (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2352-3964 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2352396424002044; https://doaj.org/toc/2352-3964 |
| DOI: | 10.1016/j.ebiom.2024.105169 |
| URL الوصول: | https://doaj.org/article/ca6c002425664b6696815b2618ecc3f3 |
| رقم الأكسشن: | edsdoj.6c002425664b6696815b2618ecc3f3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 23523964 |
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| DOI: | 10.1016/j.ebiom.2024.105169 |