Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds

التفاصيل البيبلوغرافية
العنوان:	Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds
المؤلفون:	Burair A. Alsaihati, Kun-Lin Ho, Joshua Watson, Yuan Feng, Tianfang Wang, Kevin K. Dobbin, Shaying Zhao
المصدر:	Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:	Nature Portfolio, 2021.
سنة النشر:	2021
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Genomic studies of canine tumours have been done for individual cancer types or dog breeds. Here the authors analyse canine tumour genomics data across multiple breeds and cancer types, finding that mutational burden is associated with TP53 mutations and that Golden Retrievers are enriched for particular signatures.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-021-24836-9
URL الوصول:	https://doaj.org/article/e6c541ef0f1e4b92a51650df14158fb0
رقم الأكسشن:	edsdoj.6c541ef0f1e4b92a51650df14158fb0
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-021-24836-9