دورية أكاديمية

Visualizing Frailty: Exploring Radiographical Measures of Frailty in Trauma Patients

التفاصيل البيبلوغرافية
العنوان: Visualizing Frailty: Exploring Radiographical Measures of Frailty in Trauma Patients
المؤلفون: Omolola Fakunle, Meet Patel, Victoria G. Kravets, Adam Singer, Robert Hernandez-Irizarry, Mara L. Schenker
المصدر: Journal of Acute Care Surgery, Vol 11, Iss 3, Pp 121-128 (2021)
بيانات النشر: Korean Society of Acute Care Surgery, 2021.
سنة النشر: 2021
المجموعة: LCC:Surgery
مصطلحات موضوعية: abdomen, frailty, injury, radiology, sarcopenia, trauma, Surgery, RD1-811
الوصف: Purpose This study assessed the relationship of core muscle sarcopenia, myosteatosis, and L1 attenuation to the 5-factor modified frailty index (mFI-5), discharge disposition, and post-admission complications in orthopedic and general trauma patients. It was hypothesized that reduced sarcopenia, L1 attenuation, and increased myosteatosis is associated with higher mFI-5 scores (≥ 0.3), discharge into care, and increased post-admission complications. Methods This prospective cohort study was performed at a Level 1 trauma center. Patients were surveyed and metrics of the mFI-5 were used. Frail was categorized as a mFI-5 score ≥ 0.3. Recent abdominal computed tomography (CT) scans were used to extract radiographical information of total psoas cross-sectional area, psoas myosteatosis, and L1 vertebrae attenuation. Results There were 140 patients who consented to the study, of which 83 had available abdomen and pelvis CT scans. The mean age was 43.19 (± 17.36), and 65% were male (n = 52). When comparing the frail (16%, n = 13) and not frail (84%, n = 70) patients, there was a significant difference in mean psoas myosteatosis (p < 0.0001) and the attenuation of the L1 vertebrae (p < 0.001). On multivariate analysis when accounting for age, myosteatosis of the psoas muscles was predictive of an mFI-5 score ≥ 0.3. Conclusion The findings suggest that myosteatosis and L1 attenuation are associated with frailty indices (mFI-5) after traumatic injury. Future studies are needed to prospectively assess the validity of both radiographical and index-based markers of frailty in predicting post-traumatic complications, mortality, and hospital utilization.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2288-5862
2288-9582
Relation: http://www.jacs.or.kr/upload/pdf/jacs-2021-11-3-121.pdf; https://doaj.org/toc/2288-5862; https://doaj.org/toc/2288-9582
DOI: 10.17479/jacs.2021.11.3.121
URL الوصول: https://doaj.org/article/c6dd80abd975457da05757e47171d383
رقم الأكسشن: edsdoj.6dd80abd975457da05757e47171d383
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22885862
22889582
DOI:10.17479/jacs.2021.11.3.121