دورية أكاديمية
Nonenzymatic Hydrogen Peroxide Detection Using Surface-Enhanced Raman Scattering of Gold–Silver Core–Shell-Assembled Silica Nanostructures
| العنوان: | Nonenzymatic Hydrogen Peroxide Detection Using Surface-Enhanced Raman Scattering of Gold–Silver Core–Shell-Assembled Silica Nanostructures |
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| المؤلفون: | Xuan-Hung Pham, Bomi Seong, Sungje Bock, Eunil Hahm, Kim-Hung Huynh, Yoon-Hee Kim, Wooyeon Kim, Jaehi Kim, Dong-Eun Kim, Bong-Hyun Jun |
| المصدر: | Nanomaterials, Vol 11, Iss 10, p 2748 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | surface-enhanced Raman scattering, gold–silver core–shell, gold–silver core–shell-assembled silica nanostructure, hydrogen peroxide, peroxidase-mimicking catalytic activity, 3,3,5,5-tetramethylbenzidine, Chemistry, QD1-999 |
| الوصف: | Hydrogen peroxide (H2O2) plays important roles in cellular signaling and in industry. Thus, the accurate detection of H2O2 is critical for its application. Unfortunately, the direct detection of H2O2 by surface-enhanced Raman spectroscopy (SERS) is not possible because of its low Raman cross section. Therefore, the detection of H2O2 via the presence of an intermediary such as 3,3,5,5-tetramethylbenzidine (TMB) has recently been developed. In this study, the peroxidase-mimicking activity of gold–silver core–shell-assembled silica nanostructures (SiO2@Au@Ag alloy NPs) in the presence of TMB was investigated using SERS for detecting H2O2. In the presence of H2O2, the SiO2@Au@Ag alloy catalyzed the conversion of TMB to oxidized TMB, which was absorbed onto the surface of the SiO2@Au@Ag alloy. The SERS characteristics of the alloy in the TMB–H2O2 mixture were investigated. The evaluation of the SERS band to determine the H2O2 level utilized the SERS intensity of oxidized TMB bands. Moreover, the optimal conditions for H2O2 detection using SiO2@Au@Ag alloy included incubating 20 µg/mL SiO2@Au@Ag alloy NPs with 0.8 mM TMB for 15 min and measuring the Raman signal at 400 µg/mL SiO2@Au@Ag alloy NPs. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 11102748 2079-4991 |
| Relation: | https://www.mdpi.com/2079-4991/11/10/2748; https://doaj.org/toc/2079-4991 |
| DOI: | 10.3390/nano11102748 |
| URL الوصول: | https://doaj.org/article/6dd91e48c97a4318b73e28ee56aee3e8 |
| رقم الأكسشن: | edsdoj.6dd91e48c97a4318b73e28ee56aee3e8 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 11102748 20794991 |
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| DOI: | 10.3390/nano11102748 |