دورية أكاديمية
Generation of ventilation/perfusion ratio map in surgical patients by dual-energy CT after xenon inhalation and intravenous contrast media
| العنوان: | Generation of ventilation/perfusion ratio map in surgical patients by dual-energy CT after xenon inhalation and intravenous contrast media |
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| المؤلفون: | Kohei Aoki, Yotaro Izumi, Wataru Watanabe, Yuji Shimizu, Hisato Osada, Norinari Honda, Toshihide Itoh, Mitsuo Nakayama |
| المصدر: | Journal of Cardiothoracic Surgery, Vol 13, Iss 1, Pp 1-10 (2018) |
| بيانات النشر: | BMC, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Surgery LCC:Anesthesiology |
| مصطلحات موضوعية: | Dual energy CT, Xenon CT, Perfusion CT, Ventilation perfusion ratio, Surgery, RD1-811, Anesthesiology, RD78.3-87.3 |
| الوصف: | Abstract Background While many studies have evaluated the change in lung volume before and after lung resection and correlated this with pulmonary function test results, there is very little evidence on the changes in ventilation perfusion ratio (V/Q) before versus after lung resection. In the present pilot study, we evaluated if V/Q mapping can be constructed using dual energy CT images. Methods Thirty-one lung cancer patients planned for pulmonary resection were included in this study. To evaluate ventilation, Xenon-enhanced CT was performed. This was immediately followed by perfusion CT. The two images were registered manually as well as using dedicated softwares, and division between ventilation pixels and perfusion pixels were done to produce the V/Q map. Also, in order to characterize the distribution of the V/Q, the following numerical indices were calculated; mean, median, mode, standard deviation (SD), coefficient of variation (CV), skewness, kurtosis, and fractal dimension (FD). Pulmonary function tests and blood gas parameters were measured using standard institutional procedures. Results In the whole group, VC, %VC, and FEV1 decreased significantly after resection. FEV1.0% was increased significantly after resection. No significant changes were seen in PaO2, PaCO2, and DLCO/VA before and after resection. The mean, median, mode, SD, skewness, kurtosis and FD of the V/Q did not change significantly before and after resection. A marginal but significant decrease in CV was seen before versus after resection. Conclusions Overall, it was considered that the V/Q maps could be adequately generated in this study. With further accumulation of data, V/Q map generated by dual energy CT may become one of the potentially useful tools for functional lung imaging. Trial registration This trial was registered in University Medical Information Network in Japan (UMIN000010023) on 13Feb2013. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1749-8090 |
| Relation: | http://link.springer.com/article/10.1186/s13019-018-0737-2; https://doaj.org/toc/1749-8090 |
| DOI: | 10.1186/s13019-018-0737-2 |
| URL الوصول: | https://doaj.org/article/e6efc3998d2348f382980a5aa984ba15 |
| رقم الأكسشن: | edsdoj.6efc3998d2348f382980a5aa984ba15 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 17498090 |
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| DOI: | 10.1186/s13019-018-0737-2 |