دورية أكاديمية
Considerable Genetic Diversity of Trichomonas vaginalis Clinical Isolates in a Targeted Population in South of Iran
| العنوان: | Considerable Genetic Diversity of Trichomonas vaginalis Clinical Isolates in a Targeted Population in South of Iran |
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| المؤلفون: | Razieh TAVAKOLI OLIAEE, Zahra BABAEI, Gholam Reza HATAM, Amir TAVAKOLI KARESHK, Hosein MAHMOUDVAND, Arghavan VAFAFAR, Naser ZIAALI |
| المصدر: | Iranian Journal of Parasitology, Vol 12, Iss 2 (2017) |
| بيانات النشر: | Tehran University of Medical Sciences, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Trichomoniasis, PCR-RFLP, Actin gene, Genotypes, Iran, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Background: The present study aimed to characterize genetically and to compare the most frequently occurring strains of Trichomonas vaginalis isolated from southern Iran.Methods: Totally, 150 vaginal swab and urine specimens were collected from symptomatic and asymptomatic women from May 2012 to Jun 2013.This study implemented a sensitive and reliable PCR-restriction fragment length polymorphism (RFLP) typing method on the actin gene. Moreover, one representative sample of each identified genotype was subjected to sequencing.Results: Twenty-four T. vaginalis isolates were positive and6 distinct electrophoretic patterns (H, E, G, I, M, N) were identified. Genotypes H and I were found to be more prevalent (50 and 37.5%) in Kerman and Shiraz, respectively. The phylogenetic analysis showed that two isolates were located as a separated clade with the other T. vaginalis isolates.Conclusion: The obtained findings showed a considerable genetic polymorphism of clinical isolates from the population studied. More studies may be warranted in future as to unveiling any possible links between a given genotype/cluster and pathogenic behavior of T. vaginalis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1735-7020 2008-238X |
| Relation: | https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1631; https://doaj.org/toc/1735-7020; https://doaj.org/toc/2008-238X |
| URL الوصول: | https://doaj.org/article/6f5df939ee144cdeba274a5db1e3dd2d |
| رقم الأكسشن: | edsdoj.6f5df939ee144cdeba274a5db1e3dd2d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17357020 2008238X |
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