دورية أكاديمية
Formulation and assessment of biological properties of garcinia indica fruit extract mouthrinse as an adjunct to oral hygiene regimen: an in vitro analysis
| العنوان: | Formulation and assessment of biological properties of garcinia indica fruit extract mouthrinse as an adjunct to oral hygiene regimen: an in vitro analysis |
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| المؤلفون: | Shravya MACHERLA, Jothi VARGHESE, Usha Y NAYAK, Varalakshmi VELAGACHERLA, Richard LOBO, Viswanatha U, Vinayak KAMATH |
| المصدر: | Journal of Applied Oral Science, Vol 32 (2024) |
| بيانات النشر: | University of São Paulo, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Dentistry |
| مصطلحات موضوعية: | Garcinia indica, Fruit extract, Mouthrinse, Turmeric mouthrinse, Gingivitis, Cytotoxicity, Staining, Substantivity, Dentistry, RK1-715 |
| الوصف: | Abstract The prevalence of gingivitis is substantial within the general population, necessitating rigorous oral hygiene maintenance. Objective This study assessed a Garcinia indica (GI) fruit extract-based mouthrinse, comparing it to a 0.1% turmeric mouthrinse and a 0.2% Chlorhexidine (CHX) mouthrinse. The evaluation encompassed substantivity, staining potential, antimicrobial efficacy and cytocompatibility. Methodology The study employed 182 tooth sections. For antimicrobial analysis, 64 extracted human teeth coated with a polymicrobial biofilm were divided into four groups, each receiving an experimental mouthrinse or serving as a control group with distilled water. Microbial reduction was assessed through colony forming units (CFU). Substantivity was evaluated on 54 human tooth sections using a UV spectrophotometer, while staining potential was examined on 64 tooth sections. Cytocompatibility was tested using colorimetric assay to determine non-toxic levels of 0.2% GI fruit extract, 0.1% Turmeric, and 0.2% CHX. Results Data were analysed with one-way ANOVA (α=0.05). Cell viability was highly significant (p0.05) at end of 12 hours. However, 0.1% Turmeric showed minimal CFU reduction (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-7765 1678-7757 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572024000100431&lng=en&tlng=en; http://www.scielo.br/pdf/jaos/v32/1678-7757-jaos-32-e20230291.pdf; https://doaj.org/toc/1678-7765 |
| DOI: | 10.1590/1678-7757-2023-0291 |
| URL الوصول: | https://doaj.org/article/6f74e138f5ac40daadbd809a6582e7eb |
| رقم الأكسشن: | edsdoj.6f74e138f5ac40daadbd809a6582e7eb |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16787765 16787757 |
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| DOI: | 10.1590/1678-7757-2023-0291 |