دورية أكاديمية
Effect of Antioxidant Flavonoids (Quercetin and Taxifolin) on Maturation of Porcine Oocytes
| العنوان: | Effect of Antioxidant Flavonoids (Quercetin and Taxifolin) on Maturation of Porcine Oocytes |
|---|---|
| المؤلفون: | Jung-Taek Kang, Joon Ho Moon, Ji-Yei Choi, Sol Ji Park, Su Jin Kim, Islam M. Saadeldin, Byeong Chun Lee |
| المصدر: | Asian-Australasian Journal of Animal Sciences, Vol 29, Iss 3, Pp 352-358 (2016) |
| بيانات النشر: | Asian-Australasian Association of Animal Production Societies, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Animal culture LCC:Animal biochemistry |
| مصطلحات موضوعية: | Maturation, Porcine Oocyte, Antioxidants, Quercetin, Reactive Oxygen Species [ROS], Animal culture, SF1-1100, Animal biochemistry, QP501-801 |
| الوصف: | Quercetin (QT) and taxifolin (TF) are structurally similar plant-derived flavonoids that have antioxidant properties and act as free radical scavengers. The objective of this study was to investigate effects of QT and TF on nuclear maturation of porcine oocytes. Effects of TF at 0, 1, 10, and 50 μg/mL on oocyte nuclear maturation (polar body extrusion) were investigated. After incubation for 44 h, there were no significant differences between the treatment and control groups except in the 50 μg/mL group which was significantly lower (59.2%, p80%). After parthenogenetic activation, further in vitro development of QT- or TF-treated vs control oocytes was investigated. A significantly higher proportion of QT-treated (1 μg/mL) oocytes developed into blastocysts compared to controls (24.3% vs 16.8%, respectively); however, cleavage rate and blastocyst cell number were not affected. The TF-treated group was not significantly different from controls. Levels of reactive oxygen species (ROS) and intracellular glutathione (GSH) in oocytes and embryos in a culture medium supplemented with QT or TF were measured. Both treatment groups had significantly lower (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1011-2367 1976-5517 |
| Relation: | http://www.ajas.info/upload/pdf/ajas-29-3-352.pdf; https://doaj.org/toc/1011-2367; https://doaj.org/toc/1976-5517 |
| DOI: | 10.5713/ajas.15.0341 |
| URL الوصول: | https://doaj.org/article/6fcf9a584b3e4b7f9382c81b19911e2c |
| رقم الأكسشن: | edsdoj.6fcf9a584b3e4b7f9382c81b19911e2c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10112367 19765517 |
|---|---|
| DOI: | 10.5713/ajas.15.0341 |