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Elevated TyG index is associated with increased risk of vitamin D deficiency among elderly patients with type 2 diabetes

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العنوان: Elevated TyG index is associated with increased risk of vitamin D deficiency among elderly patients with type 2 diabetes
المؤلفون: Qunyan Xiang, Hu Xu, Youshou Liu, Wu Huang
المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
بيانات النشر: Nature Portfolio, 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Triglyceride-glucose index, Vitamin D deficiency, Type 2 diabetes mellitus, Elderly people, Medicine, Science
الوصف: Abstract Vitamin D deficiency (VDD) is associated with increased risk of type 2 diabetes mellitus (T2DM) and insulin resistance (IR). We aimed to investigate the association between the triglyceride-glucose (TyG) index that represents IR and VDD in elderly patients with T2DM. We enrolled 572 elderly participants with T2DM in this study. TyG index was calculated as ln [fasting triglyceride (TG, mg/dL) × fasting blood glucose (mg/dL)/2]. Serum 25-hydroxyvitamin D [25(OH)D] level below 50 nmol/L was defined as VDD. The association between the TyG index and the VDD risk was evaluated by multivariate logistic regression analysis. We observed a significant decreased 25(OH)D level with the increase of the TyG index in elderly diabetic patients, and a negative correlation between the TyG index and 25(OH)D level. The participants in the highest TyG quartile had a 2.40-fold higher risk of VDD than those in the lowest TyG index quartile [OR 2.40; 95% CI 1.47–3.92; P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-024-67127-1
URL الوصول: https://doaj.org/article/6ffc2bc366a149ffb3b5a33467f42d99
رقم الأكسشن: edsdoj.6ffc2bc366a149ffb3b5a33467f42d99
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-024-67127-1