دورية أكاديمية
Interactions of the anti-tumor sesquiterpene hydroquinone avarol with DNA in vitro
| العنوان: | Interactions of the anti-tumor sesquiterpene hydroquinone avarol with DNA in vitro |
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| المؤلفون: | Vujčić Miroslava, Tufegdžić Srđan, Vujčić Zoran, Gašić Miroslav J., Sladić Dušan |
| المصدر: | Journal of the Serbian Chemical Society, Vol 72, Iss 12, Pp 1265-1269 (2007) |
| بيانات النشر: | Serbian Chemical Society, 2007. |
| سنة النشر: | 2007 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | avarol, hydroquinone, anti-tumor activity, pbr322 dna, calf thymus dna, Chemistry, QD1-999 |
| الوصف: | Changes in electrophoresis pattern after interaction of supercoiled plasmid pBR322 DNA with avarol was studied at a micromolar concentration of reactants under mild reaction conditions. Interactions of avarol with linear high-molecular CT-DNA at millimolar concentrations were analyzed by electrophoresis and UV spectrophotometry. It was observed that avarol is capable of quenching ethidium bromide fluorescence in DNA bands. An increase in the absorbance of DNA was detected. The results indicate the binding of avarol to DNA and/or modification of nucleotide bases. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0352-5139 1820-7421 |
| Relation: | https://doaj.org/toc/0352-5139; https://doaj.org/toc/1820-7421 |
| DOI: | 10.2298/JSC0712265V |
| URL الوصول: | https://doaj.org/article/70fce68b645344e88873b32ec8249440 |
| رقم الأكسشن: | edsdoj.70fce68b645344e88873b32ec8249440 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03525139 18207421 |
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| DOI: | 10.2298/JSC0712265V |