دورية أكاديمية
أعرض في EDS

A Case of Malignant Melanoma of the Uterine Cervix with Disseminated Metastases throughout the Vaginal Wall

التفاصيل البيبلوغرافية
العنوان: A Case of Malignant Melanoma of the Uterine Cervix with Disseminated Metastases throughout the Vaginal Wall
المؤلفون: Tomoko Noguchi, Nami Ota, Yasushi Mabuchi, Shigetaka Yagi, Sawako Minami, Hisako Okuhira, Yuki Yamamoto, Yasushi Nakamura, Kazuhiko Ino
المصدر: Case Reports in Obstetrics and Gynecology, Vol 2017 (2017)
بيانات النشر: Hindawi Limited, 2017.
سنة النشر: 2017
المجموعة: LCC:Gynecology and obstetrics
مصطلحات موضوعية: Gynecology and obstetrics, RG1-991
الوصف: Malignant melanoma (MM) in the female genital tract accounts for less than 2% of all melanomas, and the vast majority associated occur in the vulva and vagina. Primary MM of the uterine cervix is extremely rare and its prognosis is very poor. We report a case of primary MM of the cervix with dissemination throughout the vaginal wall. A 66-year-old woman presented with postmenopausal bleeding. Gynecologic examination demonstrated a 2 cm polypoid blackish-pigmented tumor on the cervix with multiple small blackish-pigmented lesions throughout the vaginal wall. Cervical Pap smear cytology showed malignant melanoma. MRI and PET/CT did not detect any distant or lymph node metastases. She underwent radical hysterectomy, pelvic lymphadenectomy, and total vaginectomy. The pathological diagnosis was FIGO stage IIIA primary cervical MM. She received adjuvant chemotherapy with 6 courses of dacarbazine, but 6 months later, multiple lung metastases were detected. Despite 4 courses of anti-PD-1 antibody (nivolumab) treatment, she died of the disease 13 months after surgery.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2090-6684
2090-6692
Relation: https://doaj.org/toc/2090-6684; https://doaj.org/toc/2090-6692
DOI: 10.1155/2017/5656340
URL الوصول: https://doaj.org/article/710d2f1ec18146a0b0c5483dc8ecb2f6
رقم الأكسشن: edsdoj.710d2f1ec18146a0b0c5483dc8ecb2f6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20906684
20906692
DOI:10.1155/2017/5656340