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Neuropsychiatric profiles in patients with Alzheimer′s disease and vascular dementia

التفاصيل البيبلوغرافية
العنوان: Neuropsychiatric profiles in patients with Alzheimer′s disease and vascular dementia
المؤلفون: Tushar Kanti Bandyopadhyay, Atanu Biswas, Arijit Roy, Deb Sankar Guin, Goutam Gangopadhyay, Sujit Sarkhel, Malay Kumar Ghoshal, Asit Kumar Senapati
المصدر: Annals of Indian Academy of Neurology, Vol 17, Iss 3, Pp 325-330 (2014)
بيانات النشر: Wolters Kluwer Medknow Publications, 2014.
سنة النشر: 2014
المجموعة: LCC:Neurology. Diseases of the nervous system
مصطلحات موضوعية: Alzheimer disease, behavioral and psychological symptoms of dementia, neuropsychiatric inventory, small vessel disease, vascular dementia, Neurology. Diseases of the nervous system, RC346-429
الوصف: Background/Aims: The aim of the following study is to compare the behavioral and psychological symptoms of dementia (BPSD) in patients of Alzheimer disease (AD) and vascular dementia (VaD). Materials and Methods: We used National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer′s Disease and Related Disorders Association criteria for diagnosing AD and National Institute of Neurological Disorders and Stroke-Association International pour la Recherche et l′Enseignement en Neurosciences Criteria for diagnosing VaD. VaD cohort was further subcategorized into small vessel and large vessel disease. The severity of cognitive impairment and the BPSD were studied by means of the Clinical Dementia Rating Scale (CDR) and the Neuropsychiatric Inventory respectively. Results: We studied 50 AD and 50 VaD patients of whom 38 were small vessels and 12 were large vessels VaD. The severity of dementia was comparable in both groups. The agitation/aggression, depression/dysphoria, anxiety, apathy/indifference, irritability, aberrant motor behavior, appetite and eating behavior and night-time behaviors occurred significantly more frequently in patients with VaD than AD. We found a weak positive correlation between the CDR score and the number of neuropsychiatric symptoms per patient in both cohorts. Elation/euphoria, agitation/aggression was significantly more frequent in patients with large vessel in comparison to small vessel VaD. Conclusions: BPSD are common in both types of dementia and they are more severe in VaD than AD when the groups have similar levels of cognitive impairment.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0972-2327
1998-3549
Relation: http://www.annalsofian.org/article.asp?issn=0972-2327;year=2014;volume=17;issue=3;spage=325;epage=330;aulast=Bandyopadhyay; https://doaj.org/toc/0972-2327; https://doaj.org/toc/1998-3549
DOI: 10.4103/0972-2327.138520
URL الوصول: https://doaj.org/article/7138750baea04cc7ad717f08bb3b989c
رقم الأكسشن: edsdoj.7138750baea04cc7ad717f08bb3b989c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:09722327
19983549
DOI:10.4103/0972-2327.138520