التفاصيل البيبلوغرافية
العنوان:
Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXRα
المؤلفون:
Liqun Chen , Alexander E. Aleshin , Gulimiran Alitongbieke , Yuqi Zhou , Xindao Zhang , Xiaohong Ye , Mengjie Hu , Gaoang Ren , Ziwen Chen , Yue Ma , Duo Zhang , Shuai Liu , Weiwei Gao , Lijun Cai , Lingjuan Wu , Zhiping Zeng , Fuquan Jiang , Jie Liu , Hu Zhou , Gregory Cadwell , Robert C. Liddington , Ying Su , Xiao-kun Zhang
المصدر:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
بيانات النشر:
Nature Portfolio, 2017.
سنة النشر:
2017
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
The transcription factor retinoid X receptor-alpha (RXRα) can also form homotetramers. Here the authors show that the anti-cancer agent K-80003 selectively inhibits the nongenomic action of N-terminally-cleaved RXRα in tumour cells by stabilizing its tetramerization but not that of full-length RXRα.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/ncomms16066
URL الوصول:
https://doaj.org/article/71d7bb2769b44bccb25ef396c7774a55
رقم الأكسشن:
edsdoj.71d7bb2769b44bccb25ef396c7774a55
قاعدة البيانات:
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