دورية أكاديمية
ANP32E induces tumorigenesis of triple‐negative breast cancer cells by upregulating E2F1
| العنوان: | ANP32E induces tumorigenesis of triple‐negative breast cancer cells by upregulating E2F1 |
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| المؤلفون: | Zhenchong Xiong, Liping Ye, He Zhenyu, Fengyan Li, Yahui Xiong, Chuyong Lin, Xianqiu Wu, Guangzheng Deng, Wei Shi, Libing Song, Zhongyu Yuan, Xi Wang |
| المصدر: | Molecular Oncology, Vol 12, Iss 6, Pp 896-912 (2018) |
| بيانات النشر: | Wiley, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | ANP32E, cell cycle, E2F1, TNBC, tumorigenesis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Triple‐negative breast cancer (TNBC) lacks expression of estrogen receptor (ER), progesterone receptor, and the HER2 receptor; it is highly proliferative and becomes the deadliest forms of breast cancer. Effective prognostic methods and therapeutic targets for TNBC are required to improve patient outcomes. Here, we report that acidic nuclear phosphoprotein 32 family member E (ANP32E), which promotes cell proliferation in mammalian development, is highly expressed in TNBC cells compared to other types of breast cancer. High expression of ANP32E correlates significantly with worse overall survival (OS; P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1878-0261 1574-7891 |
| Relation: | https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261 |
| DOI: | 10.1002/1878-0261.12202 |
| URL الوصول: | https://doaj.org/article/ae7225bcfa8d49139aaf35117b0d8f1a |
| رقم الأكسشن: | edsdoj.7225bcfa8d49139aaf35117b0d8f1a |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18780261 15747891 |
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| DOI: | 10.1002/1878-0261.12202 |