دورية أكاديمية
Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort
| العنوان: | Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort |
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| المؤلفون: | Ya-Wen Lu, Chun-Chin Chang, Ruey-Hsing Chou, Wei-Ju Lee, Liang-Kung Chen, Po-Hsun Huang, Shing-Jong Lin |
| المصدر: | BMC Geriatrics, Vol 24, Iss 1, Pp 1-9 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Geriatrics |
| مصطلحات موضوعية: | Frailty, Sex difference, Fried frailty index, Geriatrics, RC952-954.6 |
| الوصف: | Abstract Background Frailty is a common geriatric syndrome related to multiple adverse outcomes. Sex differences in its prevalence and impact on mortality remain incompletely understood. Methods This study was conducted with data from the I-Lan Longitudinal Aging Study, in which community-dwelling subjects aged > 50 years without coronary artery disease or diabetes were enrolled. Sex disparities in phenotypically defined frailty and sex–morality predictor interactions were evaluated. Sex- and frailty-stratified analyses of mortality were performed. Results The sample comprised 1371 subjects (51.4% women, median age 61 years). The median follow-up period was 6.3 (interquartile range, 5.8–7.0) years. The frailty prevalence did not differ between men (5.3%) and women (5.8%). Frail individuals were older and less educated and had poorer renal function than did non-frail individuals. Body composition trends differed between sexes, regardless of frailty. Relative to non-frail men, frail men had significantly lower body mass indices (BMIs; 24.5 vs. 23.4 kg/m2, p = 0.04) and relative appendicular skeletal muscle masses (7.87 vs. 7.05 kg/m2, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1471-2318 47571489 |
| Relation: | https://doaj.org/toc/1471-2318 |
| DOI: | 10.1186/s12877-024-04785-w |
| URL الوصول: | https://doaj.org/article/735558f47571489ebcedcf80749dba8b |
| رقم الأكسشن: | edsdoj.735558f47571489ebcedcf80749dba8b |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14712318 47571489 |
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| DOI: | 10.1186/s12877-024-04785-w |