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Effectiveness of BNT162b2 Vaccine Booster against SARS-CoV-2 Infection and Breakthrough Complications, Israel

التفاصيل البيبلوغرافية
العنوان: Effectiveness of BNT162b2 Vaccine Booster against SARS-CoV-2 Infection and Breakthrough Complications, Israel
المؤلفون: Aharona Glatman-Freedman, Michal Bromberg, Yael Hershkovitz, Hanna Sefty, Zalman Kaufman, Rita Dichtiar, Lital Keinan-Boker
المصدر: Emerging Infectious Diseases, Vol 28, Iss 5, Pp 948-956 (2022)
بيانات النشر: Centers for Disease Control and Prevention, 2022.
سنة النشر: 2022
المجموعة: LCC:Medicine
LCC:Infectious and parasitic diseases
مصطلحات موضوعية: COVID-19, coronavirus disease, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, Medicine, Infectious and parasitic diseases, RC109-216
الوصف: We estimated vaccine effectiveness (VE) of the BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) booster dose against SARS-CoV-2 infection and reduction of complications (hospitalization, severe disease, and death) among breakthrough cases in persons in Israel >16 years of age for 60 years of age on week 3. VE estimates remained at these levels for 8 weeks in the 16–59 age group and 11 weeks in those >60. A slow decline followed, becoming more pronounced in the last 2–3 weeks of evaluation. Estimates in the last week of evaluation were 77.6% (95% CI 68.4%–84.2%) and 61.3% (52.5%–68.4%) for persons 16–59 years and >60 years, respectively. The more pronounced VE decline coincided with rapid increase in Omicron variant activity. Rate reduction of breakthrough complications remained moderate to high throughout the evaluation.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1080-6040
1080-6059
Relation: https://wwwnc.cdc.gov/eid/article/28/5/22-0141_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059
DOI: 10.3201/eid2805.220141
URL الوصول: https://doaj.org/article/7396ad6ae2e24184bb397a573d4de2e1
رقم الأكسشن: edsdoj.7396ad6ae2e24184bb397a573d4de2e1
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:10806040
10806059
DOI:10.3201/eid2805.220141