دورية أكاديمية

Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating

التفاصيل البيبلوغرافية
العنوان: Validation and practical use of Plan2Heat hyperthermia treatment planning for capacitive heating
المؤلفون: H. P. Kok, J. Crezee
المصدر: International Journal of Hyperthermia, Vol 39, Iss 1, Pp 952-966 (2022)
بيانات النشر: Taylor & Francis Group, 2022.
سنة النشر: 2022
المجموعة: LCC:Medical technology
مصطلحات موضوعية: Capacitive heating, hyperthermia treatment planning, Plan2Heat, Celsius TCS, Thermotron RF8, Medical technology, R855-855.5
الوصف: Background Capacitive devices are used for hyperthermia delivery, initially mainly in Asia, but nowadays also increasingly in Europe. Treatment planning can be very useful to determine the most effective patient-specific treatment set-up. This paper provides a validation of GPU-based simulations using Plan2Heat for capacitive hyperthermia devices.Methods Validation was first performed by comparing simulations with an analytical solution for a spherical object placed inside a uniform electric field. Resolution was 5, 2.5 or 1 mm. Next, simulations for homogeneous and inhomogeneous phantom setups were performed for Thermotron RF8 and Celsius TCS capacitive heating devices at 2.5 mm resolution. Also different combinations of electrode sizes were evaluated. Normalized SAR profiles were compared to phantom measurements from the literature. Possible clinical use of treatment planning was demonstrated for an anal cancer patient, evaluating different treatment set-ups in prone and supine position.Results Numerical and analytical solutions showed excellent agreement. At the center of the sphere, the error was 5.1%, 2.9% and 0.2% for a resolution of 5, 2.5 and 1 mm, respectively. Comparison of measurements and simulations for both Thermotron RF8 and Celsius TCS showed very good agreement within 5% for all phantom set-ups. Simulations were capable of accurately predicting the penetration depth; a very relevant parameter for clinical application. The patient case illustrated that planning can provide insight by comparing effectiveness of different treatment strategies.Conclusion Plan2Heat can rapidly and accurately predict heating patterns generated by capacitive devices. Thus, Plan2Heat is suitable for patient-specific treatment planning for capacitive hyperthermia.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 02656736
1464-5157
0265-6736
Relation: https://doaj.org/toc/0265-6736; https://doaj.org/toc/1464-5157
DOI: 10.1080/02656736.2022.2093996
URL الوصول: https://doaj.org/article/74717ef40e3f42a0bb3156dbb7fb0499
رقم الأكسشن: edsdoj.74717ef40e3f42a0bb3156dbb7fb0499
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:02656736
14645157
DOI:10.1080/02656736.2022.2093996