دورية أكاديمية
Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index
العنوان: | Acylated and Desacylated Ghrelin, Preptin, Leptin, and Nesfatin-1 Peptide Changes Related to the Body Mass Index |
---|---|
المؤلفون: | Yusuf Ozkan, Esra Suay Timurkan, Suleyman Aydin, İbrahim Sahin, Mustafa Timurkan, Cihan Citil, Mehmet Kalayci, Musa Yilmaz, Aziz Aksoy, Zekiye Catak |
المصدر: | International Journal of Endocrinology, Vol 2013 (2013) |
بيانات النشر: | Hindawi Limited, 2013. |
سنة النشر: | 2013 |
المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
مصطلحات موضوعية: | Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
الوصف: | This study examines the levels of acylated and desacylated ghrelin, preptin, leptin, and nesfatin-1 peptide changes related to the body mass index (BMI). The subjects were allocated to 5 groups depending on their BMIs as follows: Group I (BMI 40 kg/m2). Serum acylated and desacylated ghrelin, preptin, and leptin levels were measured by the enzyme-linked immunosorbent assay (ELISA) and nesfatin-1 was measured by the enzyme immunoassay (EIA). Desacylated ghrelin levels showed a gradual and statistically significant drop from Group I to Group V, while preptin and leptin levels exhibited a gradual and significant increase from Group I to Group IV. Serum nesfatin-1 levels gradually, but not significantly, increased from Group I to Group III and showed a significant decrease in Groups IV and V. In conclusion, leptin, preptin, and acylated ghrelin (AG) levels increased with higher BMI, whereas desacylated ghrelin (DAG) decreased and nesfatin-1 showed no clear relationship to BMI. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1687-8337 1687-8345 |
Relation: | https://doaj.org/toc/1687-8337; https://doaj.org/toc/1687-8345 |
DOI: | 10.1155/2013/236085 |
URL الوصول: | https://doaj.org/article/74fd0bd6777b4703a10e9e92332fd0d0 |
رقم الأكسشن: | edsdoj.74fd0bd6777b4703a10e9e92332fd0d0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16878337 16878345 |
---|---|
DOI: | 10.1155/2013/236085 |