PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma

التفاصيل البيبلوغرافية
العنوان:	PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma
المؤلفون:	Wen Hu, Shao-Lin Ma, Liang Qiong, Yu Du, Li-Ping Gong, Yu-Hang Pan, Li-Ping Sun, Jing-Yun Wen, Jian-Ning Chen, Xin-Yuan Guan, Chun-Kui Shao
المصدر:	iScience, Vol 27, Iss 3, Pp 109116- (2024)
بيانات النشر:	Elsevier, 2024.
سنة النشر:	2024
المجموعة:	LCC:Science
مصطلحات موضوعية:	Biochemistry, Genetics, Molecular genetics, Science
الوصف:	Summary: The serine/threonine protein phosphatase family involves series of cellular processes, such as pre-mRNA splicing. The function of one of its members, protein phosphatase, Mg2+/Mn2+ dependent 1G (PPM1G), remains unclear in hepatocellular carcinoma (HCC). Our results demonstrated that PPM1G was significantly overexpressed in HCC cells and tumor tissues compared with the normal liver tissues at both protein and RNA levels. High PPM1G expression is associated with shorter overall survival (p
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2589-0042
Relation:	http://www.sciencedirect.com/science/article/pii/S2589004224003377; https://doaj.org/toc/2589-0042
DOI:	10.1016/j.isci.2024.109116
URL الوصول:	https://doaj.org/article/754ba15a07d64915afa9b518ed26d62f
رقم الأكسشن:	edsdoj.754ba15a07d64915afa9b518ed26d62f
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	25890042
DOI:	10.1016/j.isci.2024.109116