دورية أكاديمية

The Overlapping and Distinct Roles of HAM Family Genes in Arabidopsis Shoot Meristems

التفاصيل البيبلوغرافية
العنوان: The Overlapping and Distinct Roles of HAM Family Genes in Arabidopsis Shoot Meristems
المؤلفون: Han Han, Yuan Geng, Lei Guo, An Yan, Elliot M. Meyerowitz, Xing Liu, Yun Zhou
المصدر: Frontiers in Plant Science, Vol 11 (2020)
بيانات النشر: Frontiers Media S.A., 2020.
سنة النشر: 2020
المجموعة: LCC:Plant culture
مصطلحات موضوعية: shoot development, Arabidopsis, HAIRY MERISTEM, stem cells, confocal imaging, shoot apical meristems, Plant culture, SB1-1110
الوصف: In Arabidopsis shoot apical meristems (SAMs), a well-characterized regulatory loop between WUSCHEL (WUS) and CLAVATA3 (CLV3) maintains stem cell homeostasis by regulating the balance between cell proliferation and cell differentiation. WUS proteins, translated in deep cell layers, move into the overlaying stem cells to activate CLV3. The secreted peptide CLV3 then regulates WUS levels through a ligand-receptor mediated signaling cascade. CLV3 is specifically expressed in the stem cells and repressed in the deep cell layers despite presence of the WUS activator, forming an apical-basal polarity along the axis of the SAM. Previously, we proposed and validated a hypothesis that the HAIRY MERISTEM (HAM) family genes regulate this polarity, keeping the expression of CLV3 off in interior cells of the SAM. However, the specific role of each individual member of the HAM family in this process remains to be elucidated. Combining live imaging and molecular genetics, we have dissected the conserved and distinct functions of different HAM family members in control of CLV3 patterning in the SAMs and in the de novo shoot stem cell niches as well.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-462X
Relation: https://www.frontiersin.org/article/10.3389/fpls.2020.541968/full; https://doaj.org/toc/1664-462X
DOI: 10.3389/fpls.2020.541968
URL الوصول: https://doaj.org/article/c75729db03ce46dd9b7642bcf0b98352
رقم الأكسشن: edsdoj.75729db03ce46dd9b7642bcf0b98352
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1664462X
DOI:10.3389/fpls.2020.541968