دورية أكاديمية
Safety and efficacy of pure microvascular decompression for trigeminal neuralgia
| العنوان: | Safety and efficacy of pure microvascular decompression for trigeminal neuralgia |
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| المؤلفون: | Gang SONG, Yu-hai BAO, Ge CHEN, Hong-chuan GUO, Ming-chu LI, Xu WANG, Jian-tao LIANG |
| المصدر: | Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 18, Iss 10, Pp 709-713 (2018) |
| بيانات النشر: | Tianjin Huanhu Hospital, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | Trigeminal neuralgia, Microsurgery, Recurrence, Risk factors, Regression analysis, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Objective To analyze the efficacy and safety of pure microvascular decompression (MVD) for trigeminal neuralgia (TN), and to screen related risk factors for TN recurrence. Methods A total of 286 primary TN patients underwent pure MVD. Barrow Neurological Institute (BNI) grade was used to evaluate the relief of TN before and after surgery and during the follow-up. Postoperative complications were recorded, including facial numbness of operation side, hearing loss of operation side, cerebrospinal fluid (CSF) leakage, poor wound healing, intracranial infection and hydrocephalus. The recurrence during follow-up was also recorded. Univariate and multivariate forward Logistic regression analysis were used to screen related risk factors of recurrent TN. Results Of all patients, 18 cases (6.29%) had slight facial numbness of operation side after surgery, 13 cases (4.55% ) had hearing loss of operation side after operation. One (0.35%) had CSF leakage, and was cured after lumbar cistern drainage. One (0.35%) had no wound healing, and was cured after bone wax and repairing titanium mesh were removed in the reoperation. Two cases (0.70% ) had intracranial infection and were cured by antibiotic therapy. One (0.35%) had hydrocephalus and was cured after external ventricular drainage. Of 286 patients, 26 cases (9.09%) were lost during the follow-up, 13 cases (4.55%) had no pain relief after surgery, 13 cases (4.55%) had partial pain relief after surgery and 234 cases (81.82%) had complete pain relief after surgery. The follow-up period of 234 cases was a mean of 31.29 months. During follow-up, one case (0.35%) died of heart disease, and 28 cases (9.79%) had pain recurrence. Kaplan-Meier curve showed the rate of complete pain relief was decreased with time, the recurrence rate was 5.4% one year after surgery, 15.2% 3 years after surgery, and 21.2% 5 years after surgery. Univariate and multivariate forward Logistic regression analysis showed preoperative BNI grade Ⅴ was independent risk factor for recurrence of TN (OR = 2.385, 95%CI: 1.063-5.353; P = 0.035). Conclusions Pure MVD for treating TN is safe and effective, without postoperative death or severe complications. DOI: 10.3969/j.issn.1672-6731.2018.10.003 |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Chinese |
| تدمد: | 1672-6731 |
| Relation: | http://www.cjcnn.org/index.php/cjcnn/article/view/1847; https://doaj.org/toc/1672-6731 |
| DOI: | 10.3969/j.issn.1672-6731.2018.10.003 |
| URL الوصول: | https://doaj.org/article/75adc699279d489c9db9c8e672d0032c |
| رقم الأكسشن: | edsdoj.75adc699279d489c9db9c8e672d0032c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16726731 |
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| DOI: | 10.3969/j.issn.1672-6731.2018.10.003 |