دورية أكاديمية
Factors associated with mortality in congenital malformations of the gastrointestinal tract in a tertiary center in Senegal
العنوان: | Factors associated with mortality in congenital malformations of the gastrointestinal tract in a tertiary center in Senegal |
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المؤلفون: | Florent Tshibwid A Zeng, Papa Alassane Mbaye, Doudou Gueye, Ndèye Fatou Seck, Ibrahima Bocar Wellé, Rosalie Niang, Youssouph Diedhiou, Mbaye Fall, Ndèye Aby Ndoye, Aloïse Sagna, Oumar Ndour, Gabriel Ngom |
المصدر: | World Journal of Pediatric Surgery, Vol 6, Iss 1 (2023) |
بيانات النشر: | BMJ Publishing Group, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Pediatrics LCC:Surgery |
مصطلحات موضوعية: | Pediatrics, RJ1-570, Surgery, RD1-811 |
الوصف: | Objective Patients with congenital malformations (CMs) of the gastrointestinal tract (GIT) have a very high mortality. However, the literature on the factors associated with mortality in these patients is scarce in sub-Saharan Africa. The aim of this study is to identify independent risk factors for mortality in patients with CMs of the GIT at our pediatric surgical department.Methods We conducted a retrospective analysis of cases with CMs of the GIT managed at a tertiary center from 2018 to 2021. Patients were subdivided into two groups based on the outcomes, and variables with a significant difference were analyzed by logistic regression.Results Our review included 226 patients, 63 of whom died (27.88%). Patient age ranged from 0 to 15 years. Taking into account statistical significance, mortality was more frequent in neonates than in older patients (57.30% vs 6.15%), in patients coming out of the Dakar area than in those from the Dakar area (43.75% vs 19.18%), in patients with abnormal prenatal ultrasound than in those with normal ultrasound (100% vs 26.67%), in premature children than in those born at term (78.57% vs 21.87%), in patients with an additional malformation than in those with an isolated malformation (69.23% vs 25.35%), and in those with intestinal, esophageal, duodenal and colonic atresia than in those with other diagnoses (100%, 89%, 56.25% and 50%, respectively). Referred patients died more than those who changed hospitals or came from home (55.29% vs 25% and 9.09%, respectively). On multivariable logistic regression, two independent factors of mortality were identified: presence of associated malformation [odds ratio (OR)=13.299; 95% Confidence interval (CI) 1.370 to 129.137] and diagnosis of esophageal atresia (OR=46.529; 95% CI 5.828 to 371.425).Conclusion The presence of an associated malformation or diagnosis of esophageal atresia increases mortality in patients with CMs of the GIT in our environment. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2516-5410 |
Relation: | https://wjps.bmj.com/content/6/1/e000463.full; https://doaj.org/toc/2516-5410 |
DOI: | 10.1136/wjps-2022-000463 |
URL الوصول: | https://doaj.org/article/76176a0d38714010be97a9a6d54ec9a4 |
رقم الأكسشن: | edsdoj.76176a0d38714010be97a9a6d54ec9a4 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 25165410 |
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DOI: | 10.1136/wjps-2022-000463 |