دورية أكاديمية
Evaluation of corneal sensitivity in multiple sclerosis patients
| العنوان: | Evaluation of corneal sensitivity in multiple sclerosis patients |
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| المؤلفون: | Georges Sukkarieh, Ralph Ghorayeb, Mohamad Issa, Salam Koussa, Naji Waked |
| المصدر: | Indian Journal of Ophthalmology, Vol 69, Iss 9, Pp 2421-2424 (2021) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Ophthalmology |
| مصطلحات موضوعية: | cornea, corneal sensitivity, multiple sclerosis, Ophthalmology, RE1-994 |
| الوصف: | Purpose: To measure the corneal sensitivity in patients with multiple sclerosis (MS), to compare it with normal values and to study its correlation with different disease characteristics. Methods: Corneal sensitivity of 28 MS patients was compared to corneal sensitivity of 28 age- and gender-matched normal controls. Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer and was correlated to the duration, type and severity indexes of the disease. Results: Corneal sensitivity was comparable between both groups (P = 0.79). No statistically significant correlation was found between corneal sensitivity and the duration of MS (P = 0.55) nor the severity indexes of MS (expanded disability status scale [EDSS] P = 0.52, global multiple sclerosis severity score [MSSS] P = 0.64). Following subgroup analysis, only the primary progressive (PPMS) form of MS had a reduced corneal sensitivity with P = 0.023, while remittent-recurrent (RRMS), secondary progressive (SPMS), and clinically isolated (CIS) forms of MS did not have any reduction in the corneal sensitivity. “ROC curve analysis” showed an area under the curve of 0.48. Conclusion: In the exception of PPMS subtype, MS patients have similar corneal sensitivity in comparison to controls. Cochet-Bonnet esthesiometer does not seem to be a good diagnostic tool or a disease severity marker for patients with MS. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0301-4738 1998-3689 |
| Relation: | http://www.ijo.in/article.asp?issn=0301-4738;year=2021;volume=69;issue=9;spage=2421;epage=2424;aulast=Sukkarieh; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689 |
| DOI: | 10.4103/ijo.IJO_3052_20 |
| URL الوصول: | https://doaj.org/article/e7620928a522473ba59bf5077cd3b421 |
| رقم الأكسشن: | edsdoj.7620928a522473ba59bf5077cd3b421 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03014738 19983689 |
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| DOI: | 10.4103/ijo.IJO_3052_20 |