Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair

التفاصيل البيبلوغرافية
العنوان:	Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair
المؤلفون:	Emmanuele Crespan, Antonia Furrer, Marcel Rösinger, Federica Bertoletti, Elisa Mentegari, Giulia Chiapparini, Ralph Imhof, Nathalie Ziegler, Shana J. Sturla, Ulrich Hübscher, Barbara van Loon, Giovanni Maga
المصدر:	Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
بيانات النشر:	Nature Portfolio, 2016.
سنة النشر:	2016
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Oxidative stress is a common source of DNA damage and is repaired by the base excision repair machinery, including polymerase beta. Here the authors find that polymerase beta, and to a lesser extent lambda, can mistakenly incorporate ribonucleotides during synthesis.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/ncomms10805
URL الوصول:	https://doaj.org/article/763387984e1f4e0ab862ad33d073b020
رقم الأكسشن:	edsdoj.763387984e1f4e0ab862ad33d073b020
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/ncomms10805