دورية أكاديمية
Polymorphisms of exon 5, exon 7 and intron 10 of MMP2 gene and their association with wool density in Rex rabbits
| العنوان: | Polymorphisms of exon 5, exon 7 and intron 10 of MMP2 gene and their association with wool density in Rex rabbits |
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| المؤلفون: | S.J. Chen, Y.J. Liu, T. Liu, B.J. Chen, Z.L. Gu |
| المصدر: | World Rabbit Science, Vol 25, Iss 2, Pp 181-184 (2017) |
| بيانات النشر: | Universitat Politècnica de València, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Animal culture LCC:Veterinary medicine |
| مصطلحات موضوعية: | Rex rabbit, MMP2 gene, SNPs, fur, wool density, Animal culture, SF1-1100, Veterinary medicine, SF600-1100 |
| الوصف: | Wool density is an important index that influences Rex rabbit fur quality. In our earlier studies, we found some important differentially expressed genes in different wool density of Rex rabbit by cDNA microarray. Based on the outcome, we conducted an association study to identify single nucleotide polymorphisms (SNPs) of exon 1, 5, 7 and 10 of matrix metalloproteinase-2 (MMP2) gene and their ligands associated with wool density. The results showed that exon 1 and exon 10 of MMP2 gene did not occur mutation in 100 Rex rabbits, meanwhile 3 SNPs were identified in exon 5, exon 7 and intron 10 of MMP2 gene sequence respectively, the 3 mutation sites were as follows: MMP2-exon 5-26C/G, MMP2-exon 7-101C/T and MMP2-intron 10-6C/T. The 3 SNPs were all in Hardy-Weinberg equilibrium. Phenotypic correlation analysis results showed the 3 mutations lacked significant associations (P>0.05) with the wool density. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1257-5011 1989-8886 |
| Relation: | https://polipapers.upv.es/index.php/wrs/article/view/6514; https://doaj.org/toc/1257-5011; https://doaj.org/toc/1989-8886 |
| DOI: | 10.4995/wrs.2017.6514 |
| URL الوصول: | https://doaj.org/article/764f17686ae5430abc33c07999e2c6fd |
| رقم الأكسشن: | edsdoj.764f17686ae5430abc33c07999e2c6fd |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12575011 19898886 |
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| DOI: | 10.4995/wrs.2017.6514 |