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Indoor metabolites and chemicals outperform microbiome in classifying childhood asthma and allergic rhinitis

التفاصيل البيبلوغرافية
العنوان: Indoor metabolites and chemicals outperform microbiome in classifying childhood asthma and allergic rhinitis
المؤلفون: Yu Sun, Hao Tang, Shuang Du, Yang Chen, Zheyuan Ou, Mei Zhang, Zhuoru Chen, Zhiwei Tang, Dongjun Zhang, Tianyi Chen, Yanyi Xu, Jiufeng Li, Dan Norback, Jamal Hisham Hashim, Zailina Hashim, Jie Shao, Xi Fu, Zhuohui Zhao
المصدر: Eco-Environment & Health, Vol 2, Iss 4, Pp 208-218 (2023)
بيانات النشر: Elsevier, 2023.
سنة النشر: 2023
المجموعة: LCC:Ecology
LCC:Environmental sciences
مصطلحات موضوعية: Dust, Environmental classifier, Home, Indoor, Allergy, Ecology, QH540-549.5, Environmental sciences, GE1-350
الوصف: Indoor microorganisms impact asthma and allergic rhinitis (AR), but the associated microbial taxa often vary extensively due to climate and geographical variations. To provide more consistent environmental assessments, new perspectives on microbial exposure for asthma and AR are needed. Home dust from 97 cases (32 asthma alone, 37 AR alone, 28 comorbidity) and 52 age- and gender-matched controls in Shanghai, China, were analyzed using high-throughput shotgun metagenomic sequencing and liquid chromatography-mass spectrometry. Homes of healthy children were enriched with environmental microbes, including Paracoccus, Pseudomonas, and Psychrobacter, and metabolites like keto acids, indoles, pyridines, and flavonoids (astragalin, hesperidin) (False Discovery Rate
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2772-9850
Relation: http://www.sciencedirect.com/science/article/pii/S2772985023000406; https://doaj.org/toc/2772-9850
DOI: 10.1016/j.eehl.2023.08.001
URL الوصول: https://doaj.org/article/76740c32f8c74ff09a3dd77732525336
رقم الأكسشن: edsdoj.76740c32f8c74ff09a3dd77732525336
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:27729850
DOI:10.1016/j.eehl.2023.08.001