دورية أكاديمية
Toward Developing a Preventive MERS-CoV Vaccine—Report from a Workshop Organized by the Saudi Arabia Ministry of Health and the International Vaccine Institute, Riyadh, Saudi Arabia, November 14–15, 2015
| العنوان: | Toward Developing a Preventive MERS-CoV Vaccine—Report from a Workshop Organized by the Saudi Arabia Ministry of Health and the International Vaccine Institute, Riyadh, Saudi Arabia, November 14–15, 2015 |
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| المؤلفون: | Jean-Louis Excler, Christopher J. Delvecchio, Ryan E. Wiley, Marni Williams, In-Kyu Yoon, Kayvon Modjarrad, Mohamed Boujelal, Vasee S. Moorthy, Ahmad Salah Hersi, Jerome H. Kim |
| المصدر: | Emerging Infectious Diseases, Vol 22, Iss 8, Pp - (2016) |
| بيانات النشر: | Centers for Disease Control and Prevention, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | MERS-CoV, coronavirus, animal models, vaccine, prevention, therapeutic antibodies, Medicine, Infectious and parasitic diseases, RC109-216 |
| الوصف: | Middle East respiratory syndrome (MERS) remains a serious international public health threat. With the goal of accelerating the development of countermeasures against MERS coronavirus (MERS-CoV), funding agencies, nongovernmental organizations, and researchers across the world assembled in Riyadh, Saudi Arabia, on November 14–15, 2015, to discuss vaccine development challenges. The meeting was spearheaded by the Saudi Ministry of Health and co-organized by the International Vaccine Institute, South Korea. Accelerating the development of a preventive vaccine requires a better understanding of MERS epidemiology, transmission, and pathogenesis in humans and animals. A combination of rodent and nonhuman primate models should be considered in evaluating and developing preventive and therapeutic vaccine candidates. Dromedary camels should be considered for the development of veterinary vaccines. Several vaccine technology platforms targeting the MERS-CoV spike protein were discussed. Mechanisms to maximize investment, provide robust data, and affect public health are urgently needed. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1080-6040 1080-6059 |
| Relation: | https://wwwnc.cdc.gov/eid/article/22/8/16-0229_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
| DOI: | 10.3201/eid2208.160229 |
| URL الوصول: | https://doaj.org/article/e76968a6cac344dcb5861951433ca2c4 |
| رقم الأكسشن: | edsdoj.76968a6cac344dcb5861951433ca2c4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 10806040 10806059 |
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| DOI: | 10.3201/eid2208.160229 |