دورية أكاديمية

Energy parameters and novel algorithms for an extended nearest neighbor energy model of RNA.

التفاصيل البيبلوغرافية
العنوان: Energy parameters and novel algorithms for an extended nearest neighbor energy model of RNA.
المؤلفون: Ivan Dotu, Vinodh Mechery, Peter Clote
المصدر: PLoS ONE, Vol 9, Iss 2, p e85412 (2014)
بيانات النشر: Public Library of Science (PLoS), 2014.
سنة النشر: 2014
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: We describe the first algorithm and software, RNAenn, to compute the partition function and minimum free energy secondary structure for RNA with respect to an extended nearest neighbor energy model. Our next-nearest-neighbor triplet energy model appears to lead to somewhat more cooperative folding than does the nearest neighbor energy model, as judged by melting curves computed with RNAenn and with two popular software implementations for the nearest-neighbor energy model. A web server is available at http://bioinformatics.bc.edu/clotelab/RNAenn/.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC3931620?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0085412
URL الوصول: https://doaj.org/article/a773dfda157c4725b7d792cdbe364035
رقم الأكسشن: edsdoj.773dfda157c4725b7d792cdbe364035
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0085412