دورية أكاديمية
Impact of parathyroidectomy among nondiabetic hemodialysis patients with severe hyperparathyroidism
العنوان: | Impact of parathyroidectomy among nondiabetic hemodialysis patients with severe hyperparathyroidism |
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المؤلفون: | Qing-xiu Huang, Jie Pang, Chuan-ke Shi, Xiao-wen Huang, Xiao-fang Chen, Yan-feng Luo, Hai-wen An, Jian-lin Jian, Linna Liu, Yan-lin Li |
المصدر: | Renal Failure, Vol 44, Iss 1, Pp 1160-1168 (2022) |
بيانات النشر: | Taylor & Francis Group, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Diseases of the genitourinary system. Urology |
مصطلحات موضوعية: | Parathyroidectomy, hyperparathyroidism, hemodialysis, outcome, Diseases of the genitourinary system. Urology, RC870-923 |
الوصف: | Background Parathyroidectomy (PTX) is a treatment for hyperparathyroidism (HPT) and has uncertain risks and benefits. The aim of this study was to evaluate the effect of PTX versus nonoperative treatment among nondiabetic hemodialysis patients.Methods A retrospective matched cohort study was performed. Each PTX patient was matched with one patient who had severe HPT but rejected PTX. The patients were matched by sex, birth date, date of first dialysis, nondiabetic status, and left ventricular ejection fraction. The serum markers, survival, main adverse cardiovascular and cerebrovascular event (MACCE) rates, and hospitalization were compared between the PTX patients and matched non-PTX patients.Results There were 1143 patients at our center in the Chinese National Renal Data System (CNRDS) between 2010 and 2020. Of these, 75 PTX patients were matched with 75 non-PTX patients. Rapid decreases in the mean intact parathyroid hormone, calcium and phosphorus concentrations, and a gradual increase in hemoglobin concentration were observed in the PTX group. The mortality was 2.9 per 100 patient-years in the PTX group and 10.9 per 100 patient-years in the non-PTX group (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 0886022X 1525-6049 0886-022X |
Relation: | https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049 |
DOI: | 10.1080/0886022X.2022.2098768 |
URL الوصول: | https://doaj.org/article/779e6588c882414fa0deea3f7b76e3e7 |
رقم الأكسشن: | edsdoj.779e6588c882414fa0deea3f7b76e3e7 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 0886022X 15256049 |
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DOI: | 10.1080/0886022X.2022.2098768 |