دورية أكاديمية

Impact of parathyroidectomy among nondiabetic hemodialysis patients with severe hyperparathyroidism

التفاصيل البيبلوغرافية
العنوان: Impact of parathyroidectomy among nondiabetic hemodialysis patients with severe hyperparathyroidism
المؤلفون: Qing-xiu Huang, Jie Pang, Chuan-ke Shi, Xiao-wen Huang, Xiao-fang Chen, Yan-feng Luo, Hai-wen An, Jian-lin Jian, Linna Liu, Yan-lin Li
المصدر: Renal Failure, Vol 44, Iss 1, Pp 1160-1168 (2022)
بيانات النشر: Taylor & Francis Group, 2022.
سنة النشر: 2022
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: Parathyroidectomy, hyperparathyroidism, hemodialysis, outcome, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Background Parathyroidectomy (PTX) is a treatment for hyperparathyroidism (HPT) and has uncertain risks and benefits. The aim of this study was to evaluate the effect of PTX versus nonoperative treatment among nondiabetic hemodialysis patients.Methods A retrospective matched cohort study was performed. Each PTX patient was matched with one patient who had severe HPT but rejected PTX. The patients were matched by sex, birth date, date of first dialysis, nondiabetic status, and left ventricular ejection fraction. The serum markers, survival, main adverse cardiovascular and cerebrovascular event (MACCE) rates, and hospitalization were compared between the PTX patients and matched non-PTX patients.Results There were 1143 patients at our center in the Chinese National Renal Data System (CNRDS) between 2010 and 2020. Of these, 75 PTX patients were matched with 75 non-PTX patients. Rapid decreases in the mean intact parathyroid hormone, calcium and phosphorus concentrations, and a gradual increase in hemoglobin concentration were observed in the PTX group. The mortality was 2.9 per 100 patient-years in the PTX group and 10.9 per 100 patient-years in the non-PTX group (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0886022X
1525-6049
0886-022X
Relation: https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049
DOI: 10.1080/0886022X.2022.2098768
URL الوصول: https://doaj.org/article/779e6588c882414fa0deea3f7b76e3e7
رقم الأكسشن: edsdoj.779e6588c882414fa0deea3f7b76e3e7
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:0886022X
15256049
DOI:10.1080/0886022X.2022.2098768