دورية أكاديمية
Research advances of nanomaterials for the acceleration of fracture healing
| العنوان: | Research advances of nanomaterials for the acceleration of fracture healing |
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| المؤلفون: | Mo Zhang, Fan Xu, Jingcheng Cao, Qingqing Dou, Juan Wang, Jing Wang, Lei Yang, Wei Chen |
| المصدر: | Bioactive Materials, Vol 31, Iss , Pp 368-394 (2024) |
| بيانات النشر: | KeAi Communications Co., Ltd., 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Materials of engineering and construction. Mechanics of materials LCC:Biology (General) |
| مصطلحات موضوعية: | Fracture healing, Nanomaterials, Bone defect, Delayed union, Non-union, Bone regeneration, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5 |
| الوصف: | The bone fracture cases have been increasing yearly, accompanied by the increased number of patients experiencing non-union or delayed union after their bone fracture. Although clinical materials facilitate fracture healing (e.g., metallic and composite materials), they cannot fulfill the requirements due to the slow degradation rate, limited osteogenic activity, inadequate osseointegration ability, and suboptimal mechanical properties. Since early 2000, nanomaterials successfully mimic the nanoscale features of bones and offer unique properties, receiving extensive attention. This paper reviews the achievements of nanomaterials in treating bone fracture (e.g., the intrinsic properties of nanomaterials, nanomaterials for bone defect filling, and nanoscale drug delivery systems in treating fracture delayed union). Furthermore, we discuss the perspectives on the challenges and future directions of developing nanomaterials to accelerate fracture healing. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2452-199X |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2452199X23002554; https://doaj.org/toc/2452-199X |
| DOI: | 10.1016/j.bioactmat.2023.08.016 |
| URL الوصول: | https://doaj.org/article/cda79f06a4c74dc7a4bacd50e6d00902 |
| رقم الأكسشن: | edsdoj.79f06a4c74dc7a4bacd50e6d00902 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2452199X |
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| DOI: | 10.1016/j.bioactmat.2023.08.016 |