دورية أكاديمية
A novel gelatinized barium sulfate injection method for assessment of bronchoalveolar lavage parameters
| العنوان: | A novel gelatinized barium sulfate injection method for assessment of bronchoalveolar lavage parameters |
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| المؤلفون: | Alexander R. Gross, Temitope Kehinde, Lindsey Morais, Marshall Hutchison, Joy Grise, Nada Mohamed, Varun Badami, Haroon Ahmed, Matthew J. Zdilla, Jeffrey A. Vos, Austin G. Gross, Rachel Leonard |
| المصدر: | The Clinical Respiratory Journal, Vol 18, Iss 1, Pp n/a-n/a (2024) |
| بيانات النشر: | Wiley, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | bronchoalveolar lavage, bronchoscopy, pulmonary anatomy, research, Diseases of the respiratory system, RC705-779 |
| الوصف: | Abstract Introduction Bronchoalveolar lavage (BAL) is frequently used in pulmonary medicine though it requires further optimization. Practical obstacles such as patient safety and procedural limitation have to date precluded large, controlled trials aimed at standardization of BAL procedure. Indeed, BAL guidelines are based on observational data. Innovative research methods are necessary to advance the clinical practice of BAL. Methods In our study, we evaluated the effect of injecting a gelatinized barium solution into different lobes and segments of cadaveric lungs. As the technique requires an irreversible injection into lung airspaces, it is not suitable for in vivo purposes. We measured the volume returned from BAL as well as the distribution of BAL injection via dissection. Segmental anatomic orientation was compared to a radiologist's impression of plain film radiographs taken of injected lungs. Results Mean injected volume distributions were greatest in the upper lobes and lowest in the lower lobes; mean ratios of injected volume distribution to lung lobe volume also followed this trend. Cannulated bronchi orders favored lower branches in the upper lobe and higher branches in the lower lobes. Segmental anatomy varied by the lung lobe injected and was most varied in the lower lobes. Conclusion This novel gelatinized‐barium injection technique provides a minimally complex method to yield clinically meaningful feedback on the performance of BAL. The technique is also adaptable to study of procedural parameters in the context of variable lung anatomies and pathologies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1752-699X 1752-6981 |
| Relation: | https://doaj.org/toc/1752-6981; https://doaj.org/toc/1752-699X |
| DOI: | 10.1111/crj.13721 |
| URL الوصول: | https://doaj.org/article/7a01f0315b33483f93ae67f1d28539cc |
| رقم الأكسشن: | edsdoj.7a01f0315b33483f93ae67f1d28539cc |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1752699X 17526981 |
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| DOI: | 10.1111/crj.13721 |