دورية أكاديمية
أعرض في EDS

Clinical and pathologic factors affecting lymph node yields in colorectal cancer.

التفاصيل البيبلوغرافية
العنوان: Clinical and pathologic factors affecting lymph node yields in colorectal cancer.
المؤلفون: Ta-Wen Hsu, Hsin-Ju Lu, Chang-Kuo Wei, Wen-Yao Yin, Chun-Ming Chang, Wen-Yen Chiou, Moon-Sing Lee, Hon-Yi Lin, Yu-Chieh Su, Shih-Kai Hung
المصدر: PLoS ONE, Vol 8, Iss 7, p e68526 (2013)
بيانات النشر: Public Library of Science (PLoS), 2013.
سنة النشر: 2013
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: OBJECTIVE: Lymph node yield is recommended as a benchmark of quality care in colorectal cancer. The objective of this study was to evaluate the impact of various factors upon lymph node yield and to identify independent factors associated with lymph node harvest. MATERIALS AND METHODS: The records of 162 patients with Stage I to Stage III colorectal cancers seen in one institution were reviewed. These patients underwent radical surgery as definitive therapy; high-risk patients then received adjuvant treatment. Pathologic and demographic data were recorded and analyzed. The subgroup analysis of lymph node yields was determined using a t-test and analysis of variants. Linear regression model and multivariable analysis were used to perform potential confounding and predicting variables. RESULTS: Five variables had significant association with lymph node yield after adjustment for other factors in a multiple linear regression model. These variables were: tumor size, surgical method, specimen length, and individual surgeon and pathologist. The model with these five significant variables interpreted 44.4% of the variation. CONCLUSIONS: Patients, tumor characteristics and surgical variables all influence the number of lymph nodes retrieved. Physicians are the main gatekeepers. Adequate training and optimized guidelines could greatly improve the quality of lymph node yields.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC3713001?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0068526
URL الوصول: https://doaj.org/article/7a732c71a4304eaf89890e97cdd6710d
رقم الأكسشن: edsdoj.7a732c71a4304eaf89890e97cdd6710d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0068526