دورية أكاديمية
Arbovirus surveillance in febrile patients attending selected health facilities in Rwanda
| العنوان: | Arbovirus surveillance in febrile patients attending selected health facilities in Rwanda |
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| المؤلفون: | Vincent Rusanganwa, Olivia Wesula Lwande, Brenda Bainda, Patrick I. Chiyo, Eric Seruyange, Göran Bucht, Magnus Evander |
| المصدر: | Infection Ecology & Epidemiology, Vol 14, Iss 1 (2024) |
| بيانات النشر: | Taylor & Francis Group, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: | Tick-borne viruses, mosquito-borne viruses, molecular detection, arbovirus, Rwanda, Infectious and parasitic diseases, RC109-216 |
| الوصف: | ABSTRACTArthropod-borne (arbo) viruses cause emerging diseases that affect the livelihoods of people around the world. They are linked to disease outbreaks resulting in high morbidity, mortality, and economic loss. In sub-Saharan Africa, numerous arbovirus outbreaks have been documented, but the circulation and magnitude of illness caused by these viruses during inter-epidemic periods remains unknown in many regions. In Rwanda, there is limited knowledge on the presence and distribution of arboviruses. This study aimed at determining the occurrence and distribution of selected arboviruses, i.e., chikungunya virus (CHIKV), o’nyong-nyong virus (ONNV), dengue virus (DENV), West Nile virus (WNV), Zika virus (ZIKV), Rift Valley fever virus (RVFV) and Crimean-Congo haemorrhagic fever virus (CCHFV), among febrile patients visiting health centres in Rwanda. A total of 2294 dry blood spots (DBS) were collected on filter papers during August 2019 – December 2020. Reverse-transcription polymerase chain reaction (RT-PCR) was performed on samples in pools of ten, using both quantitative (DENV, ZIKV, RVFV) and conventional PCR (CHIKV, ONNV, WNV, CCHFV) with virus specific primers, followed by sequencing. Demographic data and clinical manifestations of illness were analysed. ONNV infection was detected in 12 of 230 pools (5.2%) and ZIKV in three pools (1.3%). The other arboviruses were not detected. All ONNV cases were found in the Rwaniro health centre, while ZIKV infection was found among patients visiting the Kirinda and Zaza health centres. There was temporal variability in ONNV infections with most cases being recorded during the long dry season, while ZIKV infection occurred during both dry and wet seasons. Patients with ONNV were older and more were females. In conclusion, ONNV and ZIKV infection were detected in acute patients and can explain some of the feverish diseases in Rwanda. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 20008686 2000-8686 |
| Relation: | https://doaj.org/toc/2000-8686 |
| DOI: | 10.1080/20008686.2023.2289872 |
| URL الوصول: | https://doaj.org/article/7b1c833bb31c4d3cacf09512e32311f8 |
| رقم الأكسشن: | edsdoj.7b1c833bb31c4d3cacf09512e32311f8 |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 20008686 |
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| DOI: | 10.1080/20008686.2023.2289872 |