دورية أكاديمية
Virological and immunological efficacy of metabolically favorable antiretroviral therapy regimens in HIV patients who had no previous treatment
العنوان: | Virological and immunological efficacy of metabolically favorable antiretroviral therapy regimens in HIV patients who had no previous treatment |
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المؤلفون: | E. I. Veselova, K. A. Kocharyan, O. V. Lovacheva, G. D. Kaminskiy, A. G. Samoylova, I. A. Vasilyeva |
المصدر: | Туберкулез и болезни лёгких, Vol 98, Iss 5, Pp 24-31 (2020) |
بيانات النشر: | New Terra Publishing House, 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Diseases of the respiratory system |
مصطلحات موضوعية: | ич-инфекция, схемы арт, вирусная нагрузка, cd4, cd8 т-лимфоциты, cd4/cd8, Diseases of the respiratory system, RC705-779 |
الوصف: | The objective: to study efficacy and safety of metabolically favorable antiretroviral therapy regimens (ART), their effect on HIV RNA levels, levels of CD4, CD8 T lymphocytes, and the ratio of CD4/CD8 in HIV patients who had no previous treatment.Subjects and methods. The study included 80 patients with HIV infection who no received ART previously, 67 of them – without clinical manifestations of HIV infection, 13 – with HIV associated diseases. The virological and immunological efficacy of three ART regimens was evaluated: rilpivirine + emtricitabine + tenofovir (RPV + FTC + TDF); dolutegravir, emtricitabine, tenofovir (DTG, FTC, TDF); raltegravir, etravirine, lamivudine (RAL, ETR, 3TC) during the first 6 months of treatment.Results. By the end of the 6th month of ART, the rate of decrease of viral load compared to the initial level increased in the series RPV + FTS + TDF |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | Russian |
تدمد: | 2075-1230 2542-1506 |
Relation: | https://www.tibl-journal.com/jour/article/view/1422; https://doaj.org/toc/2075-1230; https://doaj.org/toc/2542-1506 |
DOI: | 10.21292/2075-1230-2020-98-5-24-31 |
URL الوصول: | https://doaj.org/article/e7b3043b54c94789be446d8e09c073bb |
رقم الأكسشن: | edsdoj.7b3043b54c94789be446d8e09c073bb |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20751230 25421506 |
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DOI: | 10.21292/2075-1230-2020-98-5-24-31 |