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Impacts of futile reperfusion and reperfusion injury in acute ischemic stroke

التفاصيل البيبلوغرافية
العنوان: Impacts of futile reperfusion and reperfusion injury in acute ischemic stroke
المؤلفون: Ahmed Elmadhoun, Hongrui Wang, Yuchuan Ding
المصدر: Brain Circulation, Vol 10, Iss 1, Pp 1-4 (2024)
بيانات النشر: Wolters Kluwer Medknow Publications, 2024.
سنة النشر: 2024
المجموعة: LCC:Medical technology
LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: endovascular reperfusion therapy, ineffective (futile) reperfusion, no-reflow phenomenon, thrombectomy, thrombolysis, time window, tissue window, Medical technology, R855-855.5, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Acute ischemic stroke (AIS) remains to be a challenging cerebrovascular disease. The mainstay of AIS management is endovascular reperfusion therapy, including thrombectomy and thrombolysis. However, ineffective (futile) reperfusion (FR) or reperfusion injury (RI) can be seen in a significant number of patients undergoing reperfusion strategy. In this article, we discuss two clinically relevant concepts known as “time window” and “tissue window” that can impact the clinical outcome of reperfusion therapy. We also explore patient risk factors, leading to FR and RI as well as an emerging concept of “no-reflow phenomenon” seen in ineffective reperfusion. These fundamental concepts provide insight into the clinical management of AIS patients and provide references for future research.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2455-4626
Relation: http://www.braincirculation.org/article.asp?issn=2394-8108;year=2024;volume=10;issue=1;spage=1;epage=4;aulast=Elmadhoun; https://doaj.org/toc/2455-4626
DOI: 10.4103/bc.bc_9_24
URL الوصول: https://doaj.org/article/7b3e9cde54184810834c2d5bc0a2c516
رقم الأكسشن: edsdoj.7b3e9cde54184810834c2d5bc0a2c516
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:24554626
DOI:10.4103/bc.bc_9_24