دورية أكاديمية
Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasiaAn animal experimental study
| العنوان: | Efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation for synovial hyperplasiaAn animal experimental study |
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| المؤلفون: | Qi Xu, Xiao-hui Xu, Ze-zheng Liu, Jian-bi Zhu, Huan-huan Ding, Chun-chun Jin, Zhi-han Yan |
| المصدر: | International Journal of Hyperthermia, Vol 41, Iss 1 (2024) |
| بيانات النشر: | Taylor & Francis Group, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medical technology |
| مصطلحات موضوعية: | Percutaneous radiofrequency ablation, synovial hyperplasia, animal experiment research, ultrasonography, arthritis treatment, Medical technology, R855-855.5 |
| الوصف: | Purpose This study aimed to investigate the efficacy and safety of ultrasound-guided percutaneous radiofrequency ablation (RFA) for the treatment of synovial hyperplasia in the knee joints of antigen-induced arthritis (AIA) model rabbits.Methods Forty Japanese large-eared white rabbits were divided into AIA and control groups. After successful induction of the AIA model, the knee joints were randomly assigned to RFA and non-RFA groups. The RFA group underwent ultrasound-guided RFA to treat synovial hyperplasia in the knee joint. Dynamic observation of various detection indices was conducted to evaluate the safety and effectiveness of the RFA procedure.Results Successful synovial ablation was achieved in the RFA group, with no intraoperative or perioperative mortality. Postoperative the circumference of the knee joint reached a peak before decreasing in the third week after surgery. The incidence and diameter of postoperative skin ulcers were not significantly different compared to the non-RFA group (p > .05). Anatomical examination revealed an intact intermuscular fascia around the ablated area in the RFA group. The ablated synovial tissue initially presented as a white mass, which subsequently liquefied into a milky white viscous fluid. Gross articular cartilage was observed, along with liquefied necrosis of the synovium on pathological histology and infiltration of inflammatory cells in the surrounding soft tissue.Conclusion The experimental results demonstrated that ultrasound-guided RFA of the knee in the treatment of synovial hyperplasia in AIA model animals was both effective and safe. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 02656736 1464-5157 0265-6736 |
| Relation: | https://doaj.org/toc/0265-6736; https://doaj.org/toc/1464-5157 |
| DOI: | 10.1080/02656736.2024.2328113 |
| URL الوصول: | https://doaj.org/article/c7b5bada56234b2c85ee935d29e8d9be |
| رقم الأكسشن: | edsdoj.7b5bada56234b2c85ee935d29e8d9be |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 02656736 14645157 |
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| DOI: | 10.1080/02656736.2024.2328113 |