دورية أكاديمية
The combination of 13N-ammonia and 11C-methionine in differentiation of residual/recurrent pituitary adenoma from the pituitary gland remnant after trans-sphenoidal Adenomectomy
العنوان: | The combination of 13N-ammonia and 11C-methionine in differentiation of residual/recurrent pituitary adenoma from the pituitary gland remnant after trans-sphenoidal Adenomectomy |
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المؤلفون: | Fangling Zhang, Qiao He, Ganhua Luo, Yali Long, Ruocheng Li, Lei Ding, Xiangsong Zhang |
المصدر: | BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021) |
بيانات النشر: | BMC, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Residual/recurrent pituitary adenoma, Pituitary gland remnant, 13N-ammonia, 11C-methionine, PET/CT, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Abstract Background This study aimed to assess the clinical usefulness of 13N-ammonia and 11C- Methionine (MET) positron emission tomography (PET)/ computed tomography (CT) in the differentiation of residual/recurrent pituitary adenoma (RPA) from the pituitary gland remnant (PGR) after trans-sphenoidal adenomectomy. Methods Between June 2012 and December 2019, a total of 19 patients with a history of trans-sphenoidal adenomectomy before PET/CT scans and histological confirmation of RPA after additional surgery in our hospital were enrolled in this study. Images were interpreted by visual evaluation and semi-quantitative analysis. In semi-quantitative analysis, the maximum standard uptake value (SUVmax) of the target and gray matter was measured and the target uptake/gray matter uptake (T/G) ratio was calculated. Results The T/G ratios of 13N-ammonia were significantly higher in PGR than RPA (1.58 ± 0.69 vs 0.63 ± 1.37, P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1471-2407 07277695 |
Relation: | https://doaj.org/toc/1471-2407 |
DOI: | 10.1186/s12885-021-08574-1 |
URL الوصول: | https://doaj.org/article/c7c0727769594f4b9c63d6d2eb34e7d0 |
رقم الأكسشن: | edsdoj.7c0727769594f4b9c63d6d2eb34e7d0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14712407 07277695 |
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DOI: | 10.1186/s12885-021-08574-1 |