دورية أكاديمية
Whortleberry protects kidney against the cisplatin-induced nephrotoxicity: an experimental study
| العنوان: | Whortleberry protects kidney against the cisplatin-induced nephrotoxicity: an experimental study |
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| المؤلفون: | Huseyin Eren, Hasan Riza Aydin, Levent Tumkaya, Ilke Onur Kazaz, Yildiray Kalkan, Seher Nazli Kazaz, Tolga Mercantepe, Mustafa Ozan Horsanali, Adnan Yilmaz |
| المصدر: | Renal Failure, Vol 40, Iss 1, Pp 466-474 (2018) |
| بيانات النشر: | Taylor & Francis Group, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | Cisplatin, nephrotoxicity, kidney, total antioxidant status, total oxidant status, whortleberry, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Purpose: This study investigated the antioxidant effects of whortleberry against cisplatin-induced nephrotoxicity in rats. Material and methods: This study included 48 female Sprague–Dawley rats weighing 263.68 ± 8.29 g. The rats were divided into the following six groups, with eight rats in each group: control, ethanol control, whortleberry control, cisplatin control, 16 mg/kg cisplatin +100 mg/kg whortleberry, and 16 mg/kg cisplatin +200 mg/kg whortleberry groups. Biochemical analysis was performed by measuring total oxidant status and total antioxidant status, histopathological analysis was performed by calculating proximal and distal tubule areas (μm2), and immunohistochemical analysis was performed by determining anti-Caspase-3 immunostaining. Differences among the groups were examined using one-way analysis of variance, and p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0886-022X 1525-6049 0886022X |
| Relation: | https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049 |
| DOI: | 10.1080/0886022X.2018.1500292 |
| URL الوصول: | https://doaj.org/article/eedd7c7782ef46f9bcf7f647ff755597 |
| رقم الأكسشن: | edsdoj.7c7782ef46f9bcf7f647ff755597 |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 0886022X 15256049 |
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| DOI: | 10.1080/0886022X.2018.1500292 |