دورية أكاديمية
The clinical and immunological features of pediatric COVID-19 patients in China
العنوان: | The clinical and immunological features of pediatric COVID-19 patients in China |
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المؤلفون: | Juan Chen, Zhen-Zhen Zhang, Yao-Kai Chen, Quan-Xin Long, Wen-Guang Tian, Hai-Jun Deng, Jie-Li Hu, Xian-Xiang Zhang, Pu-Liao, Jiang-Lin Xiang, Dao-Xin Wang, Peng Hu, Fa-Chun Zhou, Zhi-Jie Li, Hong-Mei Xu, Xue-Fei Cai, De-Qiang Wang, Yuan Hu, Ni Tang, Bei-Zhong Liu, Gui-Cheng Wu, Ai-Long Huang |
المصدر: | Genes and Diseases, Vol 7, Iss 4, Pp 535-541 (2020) |
بيانات النشر: | KeAi Communications Co., Ltd., 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Medicine (General) LCC:Genetics |
مصطلحات موضوعية: | Clinical features, COVID-19, Immune, Paediatrics, SARS-CoV-2, Medicine (General), R5-920, Genetics, QH426-470 |
الوصف: | In December 2019, the corona virus disease 2019 (COVID-19) caused by novel coronavirus (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide. Few information on clinical features and immunological profile of COVID-19 in paediatrics. The clinical features and treatment outcomes of twelve paediatric patients confirmed as COVID-19 were analyzed. The immunological features of children patients was investigated and compared with twenty adult patients. The median age was 14.5-years (range from 0.64 to 17), and six of the patients were male. The average incubation period was 8 days. Clinically, cough (9/12, 75%) and fever (7/12, 58.3%) were the most common symptoms. Four patients (33.3%) had diarrhea during the disease. As to the immune profile, children had higher amount of total T cell, CD8+ T cell and B cell but lower CRP levels than adults (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2352-3042 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2352304220300507; https://doaj.org/toc/2352-3042 |
DOI: | 10.1016/j.gendis.2020.03.008 |
URL الوصول: | https://doaj.org/article/7dbe460b976e469e8996aa86b5a6a19e |
رقم الأكسشن: | edsdoj.7dbe460b976e469e8996aa86b5a6a19e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 23523042 |
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DOI: | 10.1016/j.gendis.2020.03.008 |