دورية أكاديمية
TCD hemodynamics findings in the subacute phase of anterior circulation stroke patients treated with mechanical thrombectomy
| العنوان: | TCD hemodynamics findings in the subacute phase of anterior circulation stroke patients treated with mechanical thrombectomy |
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| المؤلفون: | Wu Tingting, Shi Zongjie, Chen Bo, Geng Yu, Pan Jie |
| المصدر: | Open Medicine, Vol 17, Iss 1, Pp 606-613 (2022) |
| بيانات النشر: | De Gruyter, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | transcranial doppler ultrasound, thrombectomy, infarction, anterior cerebral artery, stroke, Medicine |
| الوصف: | Despite mechanical thrombectomy, the prognosis for many patients with anterior circulation ischemic stroke (ACIS) remains poor. This retrospective study reports consecutive mechanical thrombectomy procedures for ACIS at our hospital over 4 years. Hemodynamics were explored using transcranial Doppler ultrasound. The functional outcome was assessed using the modified Rankin scale. A total of 121 eligible cases were included: 61 (50.4%) exhibited good outcomes (modified Rankin scale score ≤2) by day 90. The logistic regression analysis showed that ipsilateral middle cerebral artery (iMCA) systolic blood flow (SBF) (OR = 0.983, 95% CI: 0.969–0.997, P = 0.014), preoperative National Institutes of Health Stroke Scale (NIHSS)score (OR = 1.160, 95% CI: 1.067–1.261, P < 0.001), intracranial hemorrhage after therapy (OR = 19.514, 95% CI: 4.364–87.265, P < 0.001), and Alberta Stroke Program Early Computed Tomography Score (OR = 0.639, 95% CI: 0.416–0.981, P = 0.040) were independently associated with prognosis. The iMCA SBF and preoperative NIHSS score were significantly predictive of a good outcome in the receiver operating characteristic analysis. In conclusion, elevated iMCA SBF might be a prognostic indicator of a good 90-day outcome following endovascular treatment in ACIS patients treated with mechanical thrombectomy, but large prospective studies are mandatory to validate the findings of our study. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2391-5463 2022-0464 |
| Relation: | https://doaj.org/toc/2391-5463 |
| DOI: | 10.1515/med-2022-0464 |
| URL الوصول: | https://doaj.org/article/7e68d0f472de4d08a60dcfed76179fa3 |
| رقم الأكسشن: | edsdoj.7e68d0f472de4d08a60dcfed76179fa3 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23915463 20220464 |
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| DOI: | 10.1515/med-2022-0464 |