التفاصيل البيبلوغرافية
العنوان:
CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells
المؤلفون:
Myung-Chul Kim , Nicholas Borcherding , Kawther K. Ahmed , Andrew P. Voigt , Ajaykumar Vishwakarma , Ryan Kolb , Paige N. Kluz , Gaurav Pandey , Umasankar De , Theodore Drashansky , Eric Y. Helm , Xin Zhang , Katherine N. Gibson-Corley , Julia Klesney-Tait , Yuwen Zhu , Jinglu Lu , Jinsong Lu , Xian Huang , Hongrui Xiang , Jinke Cheng , Dongyang Wang , Zheng Wang , Jian Tang , Jiajia Hu , Zhengting Wang , Hua Liu , Mingjia Li , Haoyang Zhuang , Dorina Avram , Daohong Zhou , Rhonda Bacher , Song Guo Zheng , Xuefeng Wu , Yousef Zakharia , Weizhou Zhang
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Regulatory T (Treg) cells are important modulators of the tumor microenvironment. Here the authors perform transcriptome profiling of immune cells from patients with renal clear cell carcinoma to find a Treg signature that correlates with poorer prognosis, with CD177 being implicated as the main mediator for related alterations in Treg activity and tumor outcome.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/s41467-021-26091-4
URL الوصول:
https://doaj.org/article/ce7f282daf59489b9f1d9368f3849b81
رقم الأكسشن:
edsdoj.7f282daf59489b9f1d9368f3849b81
قاعدة البيانات:
Directory of Open Access Journals
Find this article in full text from Springer Verlag. 
Full Text Finder