دورية أكاديمية
Dasatinib: clinical trials and management of adverse events in imatinib resistant/intolerant chronic myeloid leukemia
| العنوان: | Dasatinib: clinical trials and management of adverse events in imatinib resistant/intolerant chronic myeloid leukemia |
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| المؤلفون: | Monika Conchon, Carla Maria Boquimpani de Moura Freitas, Maria Aparecida do Carmo Rego, José Wilson Ramos Braga Junior |
| المصدر: | Revista Brasileira de Hematologia e Hemoterapia, Vol 33, Iss 2, Pp 131-139 (2011) |
| بيانات النشر: | Elsevier, 2011. |
| سنة النشر: | 2011 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs |
| مصطلحات موضوعية: | Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Drug toxicity, Drug interactions, Gastrointestinal tract, Drug resistance, neoplasm, Pyrimidines, Interferonalpha, Piperazines, Clinical Trial, Diseases of the blood and blood-forming organs, RC633-647.5 |
| الوصف: | Dasatinib is a highly effective second generation tyrosine kinase inhibitor approved for the treatment of imatinib-resistant or intolerant chronic myeloid leukemia and Philadelphia-positive acute lymphoblastic leukemia. This article reviews the results of phase I, II and III studies and looks at the efficacy and safety of dasatinib. This review also provides practical recommendations for the management of side effects. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1516-8484 1806-0870 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000200012; https://doaj.org/toc/1516-8484; https://doaj.org/toc/1806-0870 |
| DOI: | 10.5581/1516-8484.20110034 |
| URL الوصول: | https://doaj.org/article/eda7fbfea83b4b65aa90b1fa6bb7c841 |
| رقم الأكسشن: | edsdoj.7fbfea83b4b65aa90b1fa6bb7c841 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 15168484 18060870 |
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| DOI: | 10.5581/1516-8484.20110034 |