دورية أكاديمية
Clinical characteristics and outcomes of COVID-19 infection in Chinese patients with hematologic malignancies in the Omicron era
العنوان: | Clinical characteristics and outcomes of COVID-19 infection in Chinese patients with hematologic malignancies in the Omicron era |
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المؤلفون: | Xian Li, Aiqi Zhao, Huifang Jiang, Ying Lu, Jing Le, Yaping Xie, Meiwei Hu, Hui Zeng, Jianzhi Zhao, Mei Zhou, Hui Zhou, Lili Chen, Weiguo Zhu, Guifang Ouyang, Huiqing Qiu, Songfu Jiang, Qunyi Guo, Wenbin Qian, Yun Liang |
المصدر: | Hematology, Vol 28, Iss 1 (2023) |
بيانات النشر: | Taylor & Francis Group, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Diseases of the blood and blood-forming organs |
مصطلحات موضوعية: | COVID-19, hematologic malignancy, Chinese, severe infection, clinical characteristics, outcome, Diseases of the blood and blood-forming organs, RC633-647.5 |
الوصف: | ABSTRACTPatients with hematologic malignancies are often immunodeficient and therefore have a higher risk of severe symptoms from coronavirus disease 2019 (COVID-19). We retrospectively examined a cohort of 289 patients from 16 hospitals in Zhejiang Province who had hematologic malignancies and COVID-19 during a period when the Omicron variant was predominant. Univariate analysis showed that some clinical characteristics, including elder age (P = 0.014), multiple comorbid conditions (P = 0.011), and receipt of active antineoplastic therapy (P = 0.018) were associated with an increased risk of severe COVID-19. Patients with severe/critical COVID-19 had significantly lower levels of lymphocytes and serum albumin, and significantly higher levels of D-dimer, lactate dehydrogenase, C-reactive protein, and interleukin-6 (all P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 16078454 1607-8454 |
Relation: | https://doaj.org/toc/1607-8454 |
DOI: | 10.1080/16078454.2023.2288477 |
URL الوصول: | https://doaj.org/article/8012ab8e66364dff8a566fa78cd798c5 |
رقم الأكسشن: | edsdoj.8012ab8e66364dff8a566fa78cd798c5 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 16078454 |
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DOI: | 10.1080/16078454.2023.2288477 |