Drug reaction with eosinophilia and systemic symptoms syndrome

التفاصيل البيبلوغرافية
العنوان:	Drug reaction with eosinophilia and systemic symptoms syndrome
المؤلفون:	K C Shanoj, Sneha Joseph, Padmanabha Shenoy
المصدر:	Indian Journal of Rheumatology, Vol 14, Iss 5, Pp 59-66 (2019)
بيانات النشر:	Wolters Kluwer Medknow Publications, 2019.
سنة النشر:	2019
المجموعة:	LCC:Diseases of the musculoskeletal system
مصطلحات موضوعية:	drug induced, hypereosinophilia, rash, Diseases of the musculoskeletal system, RC925-935
الوصف:	Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a delayed form of severe cutaneous adverse reaction (SCAR) seen in association with certain drugs, especially anticonvulsants and allopurinol. Unlike other SCARs, DRESS is associated with significant systemic involvement such as fever, lymphadenopathy, eosinophilia, renal failure, transaminitis, and myocarditis. Because of delayed onset of symptoms and a persistent course even after discontinuation of culprit drug, DRESS can mimic a variety of rheumatological disorders. Even though glucocorticoids are the mainstay of treatment, unlike other SCARs, DRESS is associated with a high incidence of viral reactivation, especially with members of the human Herpesviridae family. Early identification of the viral activation and prompt therapy is critical in the management of DRESS.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	0973-3698 0973-3701
Relation:	http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=5;spage=59;epage=66;aulast=Shanoj; https://doaj.org/toc/0973-3698; https://doaj.org/toc/0973-3701
DOI:	10.4103/0973-3698.272151
URL الوصول:	https://doaj.org/article/80c1abd13cbe49c9ac09a03b04bbf2e4
رقم الأكسشن:	edsdoj.80c1abd13cbe49c9ac09a03b04bbf2e4
قاعدة البيانات:	Directory of Open Access Journals

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الوصف
تدمد:	09733698 09733701
DOI:	10.4103/0973-3698.272151