دورية أكاديمية
Identification of key genes and pathways in syphilis combined with diabetes: a bioinformatics study
| العنوان: | Identification of key genes and pathways in syphilis combined with diabetes: a bioinformatics study |
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| المؤلفون: | Wei Li, Chunyi Luo, Xiaoping Xie, Yongjian Xiao, Feijun Zhao, Jialun Cai, Xiangping Zhou, Tiebing Zeng, Bo Fu, Yimou Wu, Xinhua Xiao, Shuangquan Liu |
| المصدر: | AMB Express, Vol 10, Iss 1, Pp 1-10 (2020) |
| بيانات النشر: | SpringerOpen, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Biotechnology LCC:Microbiology |
| مصطلحات موضوعية: | Treponema pallidum, Syphilis, Diabetes mellitus, Bioinformatics, Biotechnology, TP248.13-248.65, Microbiology, QR1-502 |
| الوصف: | Abstract We noticed that syphilis patients seem to be more susceptible to diabetes and the lesions often involve the kidneys, but the pathogenesis is not yet completely understood. In this study, microarray analysis was performed to investigate the dysregulated expressed genes (DEGs) in rabbit model of syphilis combined with diabetes. A total of 1045 genes were identified to be significantly differentially expressed, among which 571 were up-regulated and 474 were down-regulated (≥ 2.0fold, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2191-0855 |
| Relation: | http://link.springer.com/article/10.1186/s13568-020-01009-3; https://doaj.org/toc/2191-0855 |
| DOI: | 10.1186/s13568-020-01009-3 |
| URL الوصول: | https://doaj.org/article/811a2382e9cc45e19599fc21e6ace12e |
| رقم الأكسشن: | edsdoj.811a2382e9cc45e19599fc21e6ace12e |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 21910855 |
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| DOI: | 10.1186/s13568-020-01009-3 |