دورية أكاديمية
أعرض في EDS

Renal function in β-thalassemia major patients treated with two different iron-chelation regimes

التفاصيل البيبلوغرافية
العنوان: Renal function in β-thalassemia major patients treated with two different iron-chelation regimes
المؤلفون: Osama Tanous, Yossi Azulay, Raphael Halevy, Tal Dujovny, Neta Swartz, Raul Colodner, Ariel Koren, Carina Levin
المصدر: BMC Nephrology, Vol 22, Iss 1, Pp 1-11 (2021)
بيانات النشر: BMC, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: Thalassemia, uNAG, Iron chelation therapy, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Abstract Background Renal injury in transfusion dependent β thalassemia patients (TDT) has been attributed to iron overload, chronic anemia and iron-chelation therapy (ICT) toxicity. We studied renal function in TDT patients treated with two different ICT regimes. Patients and methods We studied 36 TDT patients: 26 received deferasirox (DFX) and 10 were treated with deferoxamine (DFO) +/− deferiprone (DFP). Results Increased uNAG was found in 30% of the DFX group vs. 10% of the DFO+/−DFP group, the mean uNAG level in the DFX group was significantly higher than in the DFO+/−DFP group, (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2369
Relation: https://doaj.org/toc/1471-2369
DOI: 10.1186/s12882-021-02630-5
URL الوصول: https://doaj.org/article/81201b27bf3347d9a8c7eebcbfd57449
رقم الأكسشن: edsdoj.81201b27bf3347d9a8c7eebcbfd57449
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712369
DOI:10.1186/s12882-021-02630-5