دورية أكاديمية
A retrospective study for long-term oncologic and obstetric outcomes in cervical intraepithelial neoplasia treated with loop electrosurgical excision procedure: focus on surgical margin and human papillomavirus
| العنوان: | A retrospective study for long-term oncologic and obstetric outcomes in cervical intraepithelial neoplasia treated with loop electrosurgical excision procedure: focus on surgical margin and human papillomavirus |
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| المؤلفون: | Angela Cho, Min-Young Kim, In-Sun Park, Chul-Min Park |
| المصدر: | BMC Women's Health, Vol 24, Iss 1, Pp 1-8 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Gynecology and obstetrics LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Loop electrosurgical excision procedure, Cervical intraepithelial neoplasia, Human papilloma virus, Margin status, Obstetric outcomes, Oncologic outcomes, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270 |
| الوصف: | Abstract Background The present study aimed to evaluate the long-term oncological and obstetric outcomes following the loop electrosurgical excision procedure (LEEP) in patients with cervical intraepithelial neoplasia (CIN) and investigate the risk factors for recurrence and preterm birth. Methods This retrospective cohort study included patients who underwent LEEP for CIN 2–3 between 2011 and 2019. Demographic information, histopathological findings, postoperative cytology, and human papillomavirus (HPV) status were collected and analyzed. The Cox proportional hazards model and Kaplan-Meier curves with the log-rank test were used for risk factor analysis. Results A total of 385 patients treated with the LEEP were analyzed. Treatment failure, including recurrence or residual disease following surgery, was observed in 13.5% of the patients. Positive surgical margins and postoperative HPV detection were independent risk factors for CIN1 + recurrence or residual disease (HR 1.948 [95%CI 1.020–3.720], p = 0.043, and HR 6.848 [95%CI 3.652–12.840], p-value |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1472-6874 |
| Relation: | https://doaj.org/toc/1472-6874 |
| DOI: | 10.1186/s12905-024-02923-5 |
| URL الوصول: | https://doaj.org/article/c819685e25f041c0807788f1a6ee3b1c |
| رقم الأكسشن: | edsdoj.819685e25f041c0807788f1a6ee3b1c |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 14726874 |
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| DOI: | 10.1186/s12905-024-02923-5 |